LEISHMANIA IN PHLEBOTOMID SANDFLIES .6. IMPORTANCE OF HINDGUT DEVELOPMENT IN DISTINGUISHING BETWEEN PARASITES OF LEISHMANIA-MEXICANA AND LEISHMANIA-BRAZILIENSIS COMPLEXES
LEISHMANIA IN PHLEBOTOMID SANDFLIES .6. IMPORTANCE OF HINDGUT DEVELOPMENT IN DISTINGUISHING BETWEEN PARASITES OF LEISHMANIA-MEXICANA AND LEISHMANIA-BRAZILIENSIS COMPLEXES
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DOI：
10.1098/rspb.1977.0141
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发表时间：
1977-01-01
期刊：
影响因子：
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通讯作者：
SHAW, JJ
中科院分区：
文献类型：
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作者：
LAINSON, R;WARD, RD;SHAW, JJ
除了在白蛉媒介的中肠和前肠中生长外，白蛉的寄生虫也在白蛉媒介中生长。Braziliensis复合体在后肠中发育，在后肠中它们主要附着于幽门壁，并且在较小程度上附着于回肠。这种发展是缺乏在生活周期的成员L。mexicana复合体，仅在中肠和前肠发育。这种差异保持在实验感染各种利什曼原虫，其中一些也在其天然载体的白蛉Lutzomyia longipalpis。因此，这种实验室培育的昆虫的发育可以作为区分L。mexicana和L.巴西复合体L.的亚种。来自新热带豪猪的hertigi没有在Lutzomyia longipalpis的后肠中发育;由于这个和其他原因，它们被从L. braziliensis复杂和放置在一组自己的。L.豚鼠的enriettii在后肠中同样不能发育。这一点，加上寄生虫的其他特征，支持它继续包括在L。墨西哥情结后肠发展的某些利什曼原虫的意义进行了讨论，特别是关于利什曼原虫属的进化。
In addition to their growth in the midgut and foregut of the sandfly vectors, parasites of the L. braziliensis complex undergo development in the hindgut, where they are predominantly attached to the wall of the pylorus and, to a lesser extent, the ileum. Such development is absent in the life-cycle of members of the L. mexicana complex, which develop only in the midgut and foregut. This difference was maintained in the sandfly Lutzomyia longipalpis experimentally infected with a variety of leishmaniae, some of which were also studied in their natural vectors. Development in this laboratory-bred insect therefore serves as a quick means of distinguishing between isolates of the L. mexicana and L. braziliensis complexes. Subspecies of L. hertigi from neotropical porcupines did not develop in the hindgut of Lutzomyia longipalpis; for this and other reasons they are removed from the L. braziliensis complex and placed in a group of their own. L. enriettii, of the guinea-pig, similarly failed to develop in the hindgut. This, with additional features of the parasite, supports its continued inclusion in the L. mexicana complex. The significance of hindgut development of certain leishmaniae is discussed, particularly with regard to the evolution of the genus Leishmania.