Enterobacter cloacae producing an uncommon class A carbapenemase, IMI-1, from Singapore
Enterobacter cloacae producing an uncommon class A carbapenemase, IMI-1, from Singapore
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DOI：
10.1099/jmm.0.053363-0
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发表时间：
2013-07-01
影响因子：
3
通讯作者：
Lin, Raymond T. P.
中科院分区：
文献类型：
--
作者：
Teo, Jeanette W. P.;La, My-Van;Lin, Raymond T. P.
在这项研究中，我们描述了一种罕见的A类碳青霉烯酶，IMI-1，从临床分离的阴沟肠杆菌的特点。该分离株对碳青霉烯类抗生素具有高度耐药，但对广谱头孢菌素类抗生素仍保持敏感性。bla（IMI-1）基因由染色体编码。IMI-1生产者的检测突出了当地临床环境中碳青霉烯酶的多样性。
In this study, we describe the characterization of an infrequently encountered class A carbapenemase, IMI-1, from a clinical Enterobacter cloacae isolate. The isolate had high levels of resistance to carbapenems but retained susceptibility to expanded-spectrum cephalosporins. The bla(IMI-1) gene was chromosomally encoded. Detection of the IMI-1 producer highlights the diversity of carbapenemases in a local clinical setting.