Intraoperative changes of transcranial Doppler velocity: Relation to arterial oxygen content and whole-blood viscosity

Intraoperative changes of transcranial Doppler velocity: Relation to arterial oxygen content and whole-blood viscosity
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DOI:
10.1016/s0301-5629(98)00135-5
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发表时间:
1999-01-01
影响因子:
2.9
通讯作者:
Albrecht, KW
Albrecht, KW
中科院分区:
医学3区
文献类型:
--
作者:
Schuurman, PR;Albrecht, KW

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研究人员对 20 名无脑血管疾病的成年人进行了与血液学显着波动相关的腹部手术,研究了动脉氧含量 (CaO2) 和粘度与大脑中动脉经颅多普勒 (TCD) 血流速度的关系,在手术前和手术后立即但输血前获取了 TCD 测量和动脉血样。基线平均速度与 CaO2 (r = -0.56)、血细胞比容 (r = -0.50)、血红蛋白 (r = -0.51) 和高剪切粘度 (r = -0.46) 之间呈负相关。术中失血后,研究了 TCD 测量值、血氧和神学因素的个体内波动。在多元回归分析中,CaO2 的变化与 TCD 值的变化关联性最强,占平均速度变化的 55%。与单独使用 CaO2 相比,添加血细胞比容和粘度无法解释更多的平均速度变化。 (C) 1998 年世界超声医学与生物学联合会。
The association of arterial oxygen content (CaO2) and viscosity with transcranial Doppler (TCD) blood flow velocity in the middle cerebral artery was studied in 20 adults without cerebrovascular disease undergoing abdominal surgery associated with significant fluctuations in hematology, TCD measurements and arterial blood samples were obtained before and directly after surgery but before blood transfusion. There was an inverse association between baseline mean velocity and CaO2 (r = -0,56), hematocrit (r = -0.50), hemoglobin (r = -0.51), and high-shear viscosity (r = -0.46), After intraoperative blood loss, intraindividual fluctuations of TCD measurements, blood oxygenation, and theologic factors were studied. In multiple regression analysis, changes in CaO2 had the strongest association with changes in TCD values, accounting for 55% of the variation in mean velocity. Addition of hematocrit and viscosity could not account for more variation in mean velocity than CaO2 alone. (C) 1998 World Federation for Ultrasound in Medicine & Biology.