Influence of cataract on optical coherence tomography image quality and retinal thickness
Influence of cataract on optical coherence tomography image quality and retinal thickness
复制标题
白内障对光学相干断层扫描图像质量和视网膜厚度的影响
DOI：
10.1136/bjo.2004.097022
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发表时间：
2006-10-01
影响因子：
4.1
通讯作者：
Verbraak, F. D.
中科院分区：
文献类型：
--
作者：
van Velthoven, M. E. J.;van der Linden, M. H.;Verbraak, F. D.
背景资料：由于光学相干断层扫描（OCT）被广泛应用于眼部病理的诊断和监测，特别是在老年人中，白内障对图像质量和黄斑视网膜厚度的影响进行了研究。方法：对29例拟行白内障手术的患者进行术前和术后OCT扫描。白内障分为核性白内障、后白内障和皮质性白内障。比较图像质量（信噪比（SNR））、信号强度和黄斑厚度的参数。结果：核性白内障（n = 12）的术前扫描信噪比（SNR/SignalStrength）高于后白内障（n = 7）和皮质性白内障（n = 10）（p < 0.004）。术后所有患者的SNR和信号强度均显著增加（p < 0.001）。SNR比信号强度更好地区分差的可接受和好的扫描（接收器工作曲线下的面积：分别为0.879和0.810）。术后黄斑厚度总体上显示出显著增加（p = 0.005），在患有后白内障的患者中最明显（p = 0.028）。结论：OCT成像受白内障的影响;术前图像质量降低，术后黄斑厚度测量值略有增加。在个体患者中，即使存在白内障，OCT扫描仍然可以可靠地进行大体临床解释。
Background: As optical coherence tomography ( OCT) is widely used for diagnosis and monitoring of ocular pathology, especially in the elderly people, the influence of cataract on image quality and macular retinal thickness was studied.Methods: In 29 patients scheduled for cataract surgery, preoperative and postoperative OCT scans were obtained. Cataracts were categorised as nuclear, posterior or cortical. Parameters for image quality ( signal-to-noise ratio ( SNR)) and signal strength and macular thickness were compared. A three-level expert grading scale was used to evaluate the discriminative abilities of SNR and signal strength.Results: Nuclear cataracts ( n = 12) provided better preoperative scans ( higher SNR/ signal strength) than posterior ( n = 7) and cortical ( n = 10) cataracts ( p < 0.004). Postoperatively SNR and signal strength increased significantly in all patients ( p < 0.001). The SNR was better at discriminating poor from acceptable and good scans than signal strength ( area under the receiver operating curve: 0.879 and 0.810, respectively). Postoperative macular thickness overall showed a significant increase ( p = 0.005), most evident in patients with posterior cataracts ( p = 0.028).Conclusions: OCT imaging is influenced by cataract; image quality is reduced preoperatively and macular thickness measurements are slightly increased postoperatively. In individual patients, OCT scans remain reliable for gross clinical interpretation, even in the presence of cataract.