TMJ osteoarthritis/osteoarthrosis and immune system factors in a Japanese sample
TMJ osteoarthritis/osteoarthrosis and immune system factors in a Japanese sample
复制标题
DOI：
10.2319/091407-438
复制
发表时间：
2008-09-01
影响因子：
3.4
通讯作者：
Davidovitch, Ze'ev
中科院分区：
文献类型：
--
作者：
Nishioka, Masato;Ioi, Hideki;Davidovitch, Ze'ev
目的：探讨日本人颞下颌关节(TMJ)骨关节炎/骨关节病(OA)与免疫系统因素的关系。材料与方法：对41例研究对象(男性7例，年龄22.0+/-3.8岁；女性34例，年龄24.8+/-6.3岁)和对照组41例(男性7例，年龄22.1+/-2.3岁；女性34例，年龄24.8+/-6.4岁)按年龄和性别进行对照分析。有关病史的信息包括局部或全身疾病，药物类型和使用的详细信息，以及过敏和哮喘的存在。牙科病史问题指的是有关过去口腔损伤的细节。结果：TMJOA的过敏发生率明显高于TMJOA(P=0.008)，其平均优势比为4.125，95%可信区间为1.446~11.769。结论：过敏可能是TMJOA的危险因素之一。
Objective: To determine whether there is an association between temporomandibular joint (TMJ) osteoarthritis/osteoarthrosis (OA) and immune system factors in a Japanese sample.Materials and Methods: The records of 41 subjects (7 men, aged 22.0 +/- 3.8 years; 34 women, aged 24.8 +/- 6.3 years) and 41 pair-matched controls (7 men, aged 22.1 +/- 2.3 years; 34 women, aged 24.8 +/- 6.4 years) based on age and gender were reviewed. Information on medical history included local or systemic diseases, details on medication type and use, and the presence of allergies and asthma. Dental history questions referred to details regarding past oral injuries. The validity of the hypothesis, defining allergies and asthma as risk factors in OA, was tested by using a logistic regression analysis.Results: The incidence of allergy was significantly higher in the TMJ OA (P = .008), with a mean odds ratio of 4.125 and a 95% confidence interval of 1.446-11.769.Conclusion: These results suggest that allergy may be a risk factor in association with TMJ OA in this Japanese sample.