Effect of breed of cattle on innate resistance to infection with Babesia bovis, B-bigemina and Anaplasma marginale
Effect of breed of cattle on innate resistance to infection with Babesia bovis, B-bigemina and Anaplasma marginale
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DOI：
10.1111/j.1751-0813.1997.tb15706.x
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发表时间：
1997-05-01
影响因子：
1.1
通讯作者：
McLellan, DJ
中科院分区：
文献类型：
--
作者：
Bock, RE;deVos, AJ;McLellan, DJ
目的评价普通牛、普通牛与印度牛杂交种和印度牛对牛巴伯螨、B联巴伯螨和边缘无形体的天然抗性，以牛巴伯螨强毒感染纯B、印度牛与印度牛杂交种、印度牛与印度牛杂交种和纯B巴伯螨，B bigemina和A marginale寄生虫。方法通过静脉内接种含有1 × 10（8）牛B寄生虫的感染血液进行连续感染，然后是B二联型然后是A边缘型。为了评估耐药性，测量寄生虫血症、直肠温度、红细胞压积和需要化疗以控制感染的一组内的数量。结果B牛感染试验表明，纯B牛对B牛感染的抵抗力显著高于其他各组，且该组均不需要治疗。fi B indicus杂交和/B indicus杂交之间没有显著差异，在这些组中分别有30%和20%的阉牛需要治疗。纯B牛公牛明显更受影响，然后在其他三个组80%需要治疗。与牛B感染相比，B二联感染产生了轻度反应，并且没有牛需要治疗。然而，纯B金牛座组比其他三个组的所有其他测量值受到的影响更大。A边缘感染后，B indicus阉牛受到中度影响，50%需要治疗，而70%的FI B indicus组，80%的/B indicus交叉组和100%的纯B金牛座组需要treatment.Conclusions所有品种的牛，范围从纯B indicus纯B金牛座可能会有严重疾病的风险，如果暴露于有毒的A边缘。结果证实，纯B indicus牛对B bovis具有相对抗性，但如果杂交牛群暴露于强毒感染，则可能存在严重死亡的显著风险。
Objective To assess the innate resistance of naive Bos taurus, Bos taurus cross Bos indicus and Bos indicus cattle to virulent Babesia bovis, B bigemina and Anaplasma marginale parasites.Design Groups of 10, pure B indicus, fi B indicus cross,/B indicus cross and pure B taurus steers were infected with virulent B bovis, B bigemina and A marginale parasites.Procedure Sequential infections were carried out by intravenous inoculation of infected blood containing 1 x 10(8) parasites of B bovis, followed by B bigemina and then A marginale. To assess resistance, measurements were made of parasitaemia, rectal temperature, packed cell volume and the number within a group requiring chemotherapy to control infection. There was a recovery period between each infection.Results Infection with B bovis showed that pure B indicus steers were significantly more resistant to B bovis infection than the other groups, with none of this group requiring treatment. There was no significant difference between fi B indicus cross and/B indicus cross with 30% and 20%, respectively, of steers in these groups requiring treatment. The pure B taurus steers were significantly more affected then those in the other three groups with 80% requiring treatment. Infections of B bigemina produced a mild response in comparison to that of B bovis and none of the steers required treatment. However, the pure B taurus group was significantly more affected than the other three groups for all other measurements. After the A marginale infection, B indicus steers were moderately affected with 50% requiring treatment, whereas 70% of the fi B indicus group, 80% of the/B indicus cross group and 100% of the pure B taurus group required treatment.Conclusions All breeds of cattle, ranging from pure B indicus to pure B taurus may be at risk of severe disease if exposed to virulent A marginale. The results confirm that pure B indicus cattle are relatively resistant to B bovis, but there could be a significant risk of severe mortalities if cross-bred herds are exposed to virulent infection.