Traditional Mexican dietary pattern and cancer risk among women of Mexican descent.
Traditional Mexican dietary pattern and cancer risk among women of Mexican descent.
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墨西哥传统饮食模式和墨西哥裔女性的癌症风险。
DOI：
10.1007/s10552-024-01849-5
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Neuhouser,MarianL
中科院分区：
文献类型：
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作者：
Loroña,NicoleC;Santiago-Torres,Margarita;Lopez-Pentecost,Melissa;Garcia,Lorena;Shadyab,AladdinH;Sun,Yangbo;Kroenke,CandyceH;Snetselaar,LindaG;Stefanick,MarciaL;Neuhouser,MarianL
PurposeTo研究协会的传统墨西哥饮食评分与风险的总，乳腺癌，和结直肠癌的墨西哥裔妇女在妇女的健康倡议（WHI）。MethodsParticipants是WHI登记谁自我认定为墨西哥裔。在研究基线时自我管理的食物频率问卷的数据用于计算MexD评分，评分越高表明对优先定义的传统墨西哥饮食（高膳食纤维，蔬菜和豆类）的依从性越高。从1993年到2020年，参与者自我报告了癌症事件，并由训练有素的医生进行了裁定。我们使用多变量调整后的考克斯比例风险模型来计算风险比（HR）和95%的置信区间（CI）。ResultsAmong 2,343名墨西哥血统的妇女（中位基线年龄：59岁），共有270例癌症（88例乳腺癌，37例结直肠癌）发生在平均随访14.4年。MexD评分的最高三分位数与所有癌症发病率的较低风险相关（HR：0.67; 95% CI 0.49-0.91; p趋势：0.01）和结直肠癌（HR：0.38; 95% CI 0.14-0.998; p趋势< 0.05），MexD评分每增加一个单位，所有癌症发病率的风险降低6%（人力资源：0.94; 95% CI 0.88-0.99）。有没有统计学显着的关联与乳腺癌的风险。ConclusionConsumption传统的墨西哥饮食与所有癌症的发病率和结直肠癌的风险显着降低。考虑到结直肠癌的患病率和墨西哥裔美国妇女人口的增长，在未来的研究中证实这些发现是重要的。
PurposeTo examine the association of a traditional Mexican diet score with risk of total, breast, and colorectal cancer among women of Mexican ethnic descent in the Women’s Health Initiative (WHI).MethodsParticipants were WHI enrollees who self-identified as being of Mexican descent. Data from food frequency questionnaires self-administered at study baseline were used to calculate the MexD score, with higher scores indicating greater adherence to an a priori-defined traditional Mexican diet (high in dietary fiber, vegetables, and legumes). Incident cancers were self-reported by participants from 1993 to 2020 and adjudicated by trained physicians. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs).ResultsAmong 2,343 Mexican descent women (median baseline age: 59 years), a total of 270 cancers (88 breast, 37 colorectal) occurred during a mean follow-up of 14.4 years. The highest tertile of MexD score was associated with a lower risk of all-cancer incidence (HR: 0.67; 95% CI 0.49–0.91; p-trend: 0.01) and colorectal cancer (HR: 0.38; 95% CI 0.14–0.998; p-trend < 0.05), with each unit increase in the MexD score associated with a 6% lower risk of all-cancer incidence (HR: 0.94; 95% CI 0.88–0.99). There was no statistically significant association with risk of breast cancer.ConclusionConsumption of a traditional Mexican diet was associated with a significantly lower risk of all-cancer incidence and colorectal cancer. Confirmation of these findings in future studies is important, given the prevalence of colorectal cancer and a growing U.S. population of women of Mexican descent.