Some observations on cortical inputs to the macaque monkey amygdala: An anterograde tracing study
Some observations on cortical inputs to the macaque monkey amygdala: An anterograde tracing study
复制标题
DOI：
10.1002/cne.10339
复制
发表时间：
2002-09
影响因子：
2.5
通讯作者：
L. Stefanacci;D. Amaral
中科院分区：
文献类型：
--
作者：
L. Stefanacci;D. Amaral
我们以前描述了起源的新皮质输入的猕猴杏仁核外侧核的基础上逆行追踪研究。在这里，我们报告的结果，从研究中，试图确认预测从几个候选传入区域使用3 H-氨基酸放射自显影作为顺行示踪剂。根据33次单独注射的结果，我们绘制了整个杏仁核皮质投射的地形分布图。颞下皮质的TE和TEO区、颞上级回的部分和小脑颗粒区主要投射到外侧核，其他杏仁核的神经支配很少或没有。相反，眶额、内侧前额叶和前扣带区主要投射到基底核和副基底核，对外侧核的神经支配很少。眶额和内侧前额叶皮质，而不是前扣带回皮质，投射到位于内侧的杏仁核区域，如皮质和内侧核，以及杏仁核周围皮质。上级颞回的无颗粒和脱颗粒核、副沟和吻侧部分投射到外侧、基底和副基底核以及位于内侧的核。从这些区域向中央核的投影特别突出。这些数据进行了讨论，在杏仁复合体内发生的感觉信息的分层处理。神经学比较杂志451：301-323，2002.© 2002 Wiley利斯公司
We have previously described the origins of neocortical inputs to the lateral nucleus of the macaque monkey amygdala based on retrograde tracing studies. Here we report results from studies that have attempted to confirm the projections from several candidate afferent regions using 3H‐amino acid autoradiography as an anterograde tracer. We have charted, based on the results of 33 separate injections, the topographic distribution of cortical projections throughout the amygdala. Areas TE and TEO of the inferotemporal cortex, portions of the superior temporal gyrus, and the granular region of the insula project primarily to the lateral nucleus, with little or no innervation of other amygdaloid nuclei. In contrast, orbitofrontal, medial prefrontal, and anterior cingulate regions project primarily to the basal and accessory basal nuclei and provide little innervation to the lateral nucleus. The orbitofrontal and medial prefrontal cortices, but not the anterior cingulate cortex, project to medially situated amygdaloid areas such as the cortical and medial nuclei and to the periamygdaloid cortex. The agranular and dysgranular insula, the parainsula, and rostral portions of the superior temporal gyrus project both to the lateral, basal, and accessory basal nuclei and to the medially situated nuclei. Projections to the central nucleus are particularly prominent from these regions. These data are discussed in relation to the hierarchical processing of sensory information that occurs within the amygdaloid complex. J. Comp. Neurol. 451:301–323, 2002. © 2002 Wiley‐Liss, Inc.