Bonelike Coatings onto Ceramics by Reactive Magnetron Sputtering
Bonelike Coatings onto Ceramics by Reactive Magnetron Sputtering
复制标题
通过反应磁控溅射在陶瓷上形成骨状涂层
DOI：
10.1111/j.1151-2916.1996.tb08111.x
复制
发表时间：
1996
影响因子：
3.9
通讯作者：
T. Umegaki
中科院分区：
文献类型：
--
作者：
K. Yamashita;T. Yagi;T. Umegaki
部分碳化羟基磷灰石钙在强陶瓷和金属表面的类骨涂层是目前生物材料科学研究的目标之一，用于开发生物活性植入材料。我们最近在CO2/Ar混合气体中采用新开发的反应性rf磁控溅射方法在陶瓷氧化铝上完成了骨状磷灰石涂层。该方法的关键是使用比羟基磷灰石的化学计量值低得多的Ca/P比的磷酸钙玻璃靶。通过XRD、EDX和FT-IR分析，发现形成了骨状的碳化羟基磷灰石钙，其中CO2-3离子占据了PO3-4的晶格位置。体外模拟体液生长实验证实了包覆陶瓷材料的生物活性，实验证明包覆陶瓷材料表面骨样晶体的生长速度远快于未碳化羟基磷灰石表面
Bonelike coating of partially carbonated, calcium hydroxyapatite onto strong ceramics and metals is one of the current objectives in biomaterials science for the development of bioactive implant materials. We recently accomplished bonelike apatite coating onto ceramic alumina by the newly developed reactive rf-magnetron sputtering method, which was undertaken in a mixed CO2/Ar gas. The key of this method is the use of calcium phosphate glass targets with much lower Ca/P ratios than the stoichiometric value of hydroxyapatite. Surface analyses by XRD, EDX, and FT-IR identified the formation of bonelike carbonated calcium hydroxyapatite, in which CO2-3 ions occupied the lattice positions of PO3-4. The bioactivity of the coated ceramic materials was confimed by in vitro experiments on the bonelike crystal growth on their surfaces in a simulated body fluid, and the growth rate on the coated layers was experimentally proved to be much faster than that on uncarbonated hydroxyapatite