Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors
Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors
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DOI：
10.1016/s0167-4781(99)00244-4
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发表时间：
2000-01-31
期刊：
影响因子：
--
通讯作者：
Osumi, T
中科院分区：
文献类型：
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作者：
Yasumo, H;Masuda, N;Osumi, T
酵母双杂交筛选发现核受体结合因子-2(NRBF-2)是过氧化体增殖物激活受体α和其他几种核受体的相互作用伙伴。当NRBF-2与异源DNA结合域连接时，NRBF-2在哺乳动物细胞和酵母中都显示出基因激活功能。(C)2000 Elsevier Science B.V.保留所有权利。
A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor a as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast. (C) 2000 Elsevier Science B.V. All rights reserved.