GENERAL CHARACTERISTICS OF SYMPATHETIC ACTIVITY IN HUMAN MUSCLE NERVES

GENERAL CHARACTERISTICS OF SYMPATHETIC ACTIVITY IN HUMAN MUSCLE NERVES
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DOI:
10.1111/j.1748-1716.1972.tb05157.x
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发表时间:
1972-01-01
期刊:
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子:
--
通讯作者:
HONGELL, A
HONGELL, A
中科院分区:
其他
文献类型:
--
作者:
DELIUS, W;HAGBARTH, KE;HONGELL, A

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多单位交感神经活动记录从肌肉神经束在正中或腓神经的休息,放松的人类受试者。的冲动,这是可逆的交感神经节阻断剂,废除分组的脉冲节奏,和一系列这样的脉冲节奏的脉冲突发定期出现在自发发生的血压降低,而暂时的血压升高与神经沉默。研究结果同意的概念,即记录的交感肌神经活动包括血管收缩冲动,其中的流出是由一个强大的相位和紧张性抑制压力反射的影响调制。从动脉脉搏波到相应的传出交感神经活动抑制的反射延迟为0.9-1.4秒,取决于记录部位。几种刺激,如突然的胸部按压,快速的深呼吸或对皮肤的电击,引起持续几秒钟的交感神经放电的短暂抑制。
Multiunit sympathetic activity was recorded from muscle nerve fascicles in the median or peroneal nerve of resting, relaxed human subjects. The impulses, which were reversibly abolished by a Sympathetic ganglion blocking agent, were grouped in the pulse rhythm, and series of such pulse rhythmic bursts of impulses regularly appeared during spontaneously occurring blood pressure reductions, whereas temporary blood pressure elevations were associated with neural silence. The findings agree with the notion that the sympathetic muscle nerve activity recorded consists of vasoconstrictor impulses, the outflow of which is modulated by a strong phasic and tonic inhibitory baroreflex influence. The reflex delay from an arterial pulse wave to the corresponding inhibition of efferent sympathetic activity was 0.9–1.4 seconds, depending on the recording site. Several stimuli, such as sudden chest compression, a rapid deep breath or an electrical shock against the skin, caused a transient inhibition of the sympathetic discharges lasting a few seconds.