Radiation-induced breaks of DNA in cultured mammalian cells.
Radiation-induced breaks of DNA in cultured mammalian cells.
复制标题
培养的哺乳动物细胞中辐射诱导的 DNA 断裂。
DOI：
10.1016/s0006-3495(69)86390-3
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发表时间：
1969
影响因子：
3.4
通讯作者：
S. Okada
中科院分区：
文献类型：
--
作者：
W. Veatch;S. Okada
对悬浮培养的小鼠白血病细胞(L5178Y)进行照射，用蔗糖梯度离心法测定DNA单链断裂和双链断裂的程度。辐射每拉德产生每个细胞(G1期)3.0个单链断裂和大约0.3个双链断裂(G1期)。
Mouse leukemic cells (L5178Y) in suspension culture were irradiated and the extent of single-strand breaks and double-strand cuts of DNA was estimated by sucrose gradient centrifugation. The radiation produced 3.0 single-strand breaks per cell (G1stage) per rad and approximately 0.3 double-strand breaks per cell (G1stage) per rad.