Prevalence of Metabolic Syndrome in Pakistan
Prevalence of Metabolic Syndrome in Pakistan
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DOI：
10.1089/met.2008.0005
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发表时间：
2008-09-01
影响因子：
2.1
通讯作者：
Shera, A. Samad
中科院分区：
文献类型：
--
作者：
Basit, Abdul;Shera, A. Samad
在过去的二十年里，患有代谢综合征的人数显著增加。由于缺乏国际上商定的定义，代谢综合征的患病率各不相同。考虑到亚洲人心血管疾病风险的增加，定义了一个较低的腰围临界值。腰围肥胖占巴基斯坦人口的46-68%，手臂脂肪和胰岛素不敏感之间有很强的联系。在研究血脂异常时，高甘油三酯血症在27-54%的人群中发现，而68-81%的人群高密度脂蛋白（HDL）水平低。50%的人被发现有患代谢综合征和高血压的高风险。由于所有这些代谢危险因素的高患病率，根据不同的定义，巴基斯坦代谢综合征的患病率据报道为18%至46%，与其他南亚国家的数据相当。因此，代谢综合征应被视为预防医学的首要目标。代谢综合征的主要管理目标是降低心血管疾病和糖尿病的风险。与生活方式相关的危险因素与代谢综合征和糖尿病有关。除非适当地设计和实施预防方案，否则我们将继续治疗大多数已经出现并发症的病例。巴基斯坦正在进行一项前瞻性的初级预防研究，这将有助于为提高公众认识战略和全国性的非传染性疾病监测和预防方案奠定基础。
Over the past two decades, there has been a striking increase in the number of people with metabolic syndrome. The prevalence of metabolic syndrome varies due to lack of an internationally agreed upon definition. Considering the increased cardiovascular risk among Asian people, a lower cutoff for waist circumference is defined. Obesity in terms of waist circumference is found to be 46-68%, of the Pakistani population, with a strong association found between arm fat and insulin insensitivity. In studying dyslipidemia, hypertriglyceridemia is found in 27-54% of the Population, whereas 68-81% have low levels of high-density lipoprotein (HDL). Fifty percent were found to be at high risk of metabolic syndrome and as being hypertensive. With the high prevalence of all of these metabolic risk factors, the prevalence of metabolic syndrome in Pakistan according to different definitions is reported to be from 18% to 46%, comparable to the data from other South Asian countries. Thus, metabolic syndrome should be considered as a prime target for preventive medicine. The primary management goals for metabolic syndrome are to reduce the risks of cardiovascular disease and diabetes. Lifestyle-related risk factors are associated with the metabolic syndrome and diabetes. Unless preventive programs are properly designed and implemented, we will continue to treat the majority of the cases after they have already developed the complications. A prospective primary prevention Study is underway in Pakistan that will help to create a base for public awareness strategies and nationwide surveillance and prevention programs against noncommunicable diseases.