Travel-related infection in European travelers, EuroTravNet 2011.
Travel-related infection in European travelers, EuroTravNet 2011.
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欧洲旅行者中与旅行相关的感染，EuroTravNet 2011。
DOI：
10.1111/jtm.12120
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发表时间：
2014
影响因子：
25.7
通讯作者：
L
中科院分区：
文献类型：
--
作者：
Warne,Ben;Weld,LeisaH;Cramer,JakobP;Field,VanessaK;Grobusch,MartinP;Caumes,Eric;Jensenius,Mogens;Gautret,Philippe;Schlagenhauf,Patricia;Castelli,Francesco;Lalloo,DavidG;Ursing,Johan;Chappuis,François;vonSonnenburg,Frank;L
背景：关于传染病输入到欧洲各地的数据有限，特别是在欧洲大陆旅行之后。方法为了调查与欧洲相关的旅行相关疾病，这些疾病可以通过旅行前干预措施加以预防，我们分析了欧洲旅游网数据库中2011年16个“西欧”中心报告的5965名患病旅行者的数据。结果54例疫苗可预防疾病，以甲型肝炎（16例）、伤寒（11例）、麻疹（8例）为主；6例（包括3例麻疹）与在“西欧”旅行有关。疟疾是最常见的感染（n = 482，占所有旅行相关发病率的8.1%）。在疟疾患者中，军人最常收到旅行前建议（95%），其次是传教、志愿者、研究或援助工作的旅行者（81%），但探访亲友（VFRs）的旅行者最不可能收到旅行前建议（21%）。绝大多数（96%）疟疾患者居住在“西欧”，但超过一半（56%）出生在其他地方。其他可通过建议和行为改变来降低发病率的重要原因包括贾第鞭毛虫病（n = 221, 3.7%）、登革热（n = 146, 2.4%）和血吸虫病（n = 131, 2.2%）。在“西欧”的206名（3.5%）旅行者中，75%是游客；疾病负担最高的是急性胃肠道感染（35%）。来自“东欧”的旅行（n = 132, 2.2%）主要与移民相关的旅行相关（53%）；在慢性传染病中，结核病是最常见的诊断（n = 20）。旅行者vsr是最大的疟疾患者群体（46%），但在这一人群中，记录在案的旅行前健康咨询率最低（20%）。总体而言，44%的非移民患病旅行者在旅行前没有收到建议。结论前往欧洲卫生中心的旅行者存在传染病负担，通过全面的旅行前建议、化学预防和疫苗接种是有可能预防的。对旅行者出血热和与迁徙相关的旅行者等高危人群进行有针对性的干预尤为重要。
BackgroundLimited data exist on infectious diseases imported to various locations in Europe, particularly after travel within the continent.MethodsTo investigate travel‐related disease relevant to Europe that is potentially preventable through pre‐travel intervention, we analyzed the EuroTravNet database of 5,965 ill travelers reported by 16 centers in “Western” Europe in 2011.ResultsThere were 54 cases of vaccine‐preventable disease, mostly hepatitis A (n = 16), typhoid fever (n = 11), and measles (n = 8); 6 cases (including 3 measles cases) were associated with travel within “Western” Europe. Malaria was the most commonly diagnosed infection (n = 482, 8.1% of all travel‐related morbidity). Among patients with malaria, the military most commonly received pre‐travel advice (95%), followed by travelers for missionary, volunteer, research, or aid work (81%) but travelers visiting friends and relatives (VFRs) were least likely to receive pre‐travel advice (21%). The vast majority (96%) of malaria patients were resident in “Western” Europe, but over half (56%) were born elsewhere. Other significant causes of morbidity, which could be reduced through advice and behavioral change, include Giardia (n = 221, 3.7%), dengue (n = 146, 2.4%), and schistosomiasis (n = 131, 2.2%). Of 206 (3.5%) travelers with exposure in “Western” Europe, 75% were tourists; the highest burden of disease was acute gastrointestinal infection (35% cases). Travel from “Eastern” Europe (n = 132, 2.2%) was largely associated with migration‐related travel (53%); among chronic infectious diseases, tuberculosis was frequently diagnosed (n = 20). Travelers VFRs contributed the largest group of malaria patients (46%), but also had the lowest documented rate of pre‐travel health advice in this subset (20%). Overall, 44% of nonimmigrant ill travelers did not receive pre‐travel advice.ConclusionThere is a burden of infectious diseases in travelers attending European health centers that is potentially preventable through comprehensive pre‐travel advice, chemoprophylaxis, and vaccination. Targeted interventions for high‐risk groups such as travelers VFRs and migration‐associated travelers are of particular importance.