Respiratory responses of vigorously exercising children to 0.12 ppm ozone exposure.
Respiratory responses of vigorously exercising children to 0.12 ppm ozone exposure.
复制标题
剧烈运动的儿童对 0.12 ppm 臭氧暴露的呼吸反应。
DOI：
10.1164/arrd.1985.132.4.875
复制
发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Collier,AM
中科院分区：
文献类型：
--
作者：
McDonnell3rd,WF;Chapman,RS;Leigh,MW;Strope,GL;Collier,AM
建议在从事正常活动时暴露于低于0.12ppm臭氧(O3)的儿童呼吸功能发生变化。由于这些研究的结果受到其他变量的干扰，如温度或其他污染物的存在，或者暴露测量的充分性受到质疑，我们在受控室环境中确定了暴露于0.12ppm臭氧的儿童的急性反应。23名8至11岁的白人男性随机暴露在清洁空气和0.12ppm臭氧中一次。暴露时间为2.5h，其中包括间歇性大强度运动2h。分别在每次暴露前和暴露后测定用力呼气量(FEV1)和咳嗽症状。与空气暴露相比，接触臭氧后FEV1显著下降，并可持续16至20小时。未发现接触臭氧引起的咳嗽明显增加。在这项研究的二次探索性分析中，测量了用力肺活量、特定呼吸道阻力、呼吸频率、潮气量和其他症状。
Changes in respiratory function have been suggested for children exposed to less than 0.12 ppm ozone (O3) while engaged in normal activities. Because the results of these studies have been confounded by other variables, such as temperature or the presence of other pollutants or have been questioned as to the adequacy of exposure measurements, we determined the acute response of children exposed to 0.12 ppm O3in a controlled chamber environment. Twenty-three white males 8 to 11 yr of age were exposed once to clean air and once to 0.12 ppm O3in random order. Exposures were for 2.5 h and included 2 h of intermittent heavy exercise. Measures of forced expiratory volume in one second (FEV1and the symptom cough were determined prior to and after each exposure. A significant decline in FEV1was found after the O3exposure compared to the air exposure, and it appeared to persist for 16 to 20 h. No significant increase in cough was found due to O3exposure. Forced vital capacity, specific airways resistance, respiratory frequency, tidal volume, and other symptoms were measured in a secondary exploratory analysis of this study.