Pulmonary function in children with idiopathic scoliosis.
Pulmonary function in children with idiopathic scoliosis.
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DOI：
10.1186/1748-7161-7-7
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发表时间：
2012-03-23
期刊：
影响因子：
--
通讯作者：
Grivas T
中科院分区：
文献类型：
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作者：
Tsiligiannis T;Grivas T
特发性脊柱侧凸是一种常见的脊柱侧凸，在身体快速生长期间，椎体发生侧向移位和旋转，对呼吸功能有许多影响。脊柱侧凸导致限制性肺病，多因素导致肺体积减少，移位胸内器官，阻碍肋骨运动并影响呼吸肌的力学。脊柱侧凸会降低胸壁和肺顺应性，导致休息时、运动和睡眠时呼吸功增加。严重的疾病可能会出现肺动脉高压和呼吸衰竭。本文综述了特发性脊柱侧凸的流行病学和解剖学特征，描述了特发性脊柱侧凸的病理生理学及其对呼吸功能的影响，介绍了肺功能检测，包括肺容量、呼吸流量和气道阻力、胸壁运动、局部通气和灌注、血气、运动反应和睡眠研究。术前肺功能检查的要求，以及各种手术方法对呼吸功能的影响也进行了讨论。
Idiopathic scoliosis, a common disorder of lateral displacement and rotation of vertebral bodies during periods of rapid somatic growth, has many effects on respiratory function. Scoliosis results in a restrictive lung disease with a multifactorial decrease in lung volumes, displaces the intrathoracic organs, impedes on the movement of ribs and affects the mechanics of the respiratory muscles. Scoliosis decreases the chest wall as well as the lung compliance and results in increased work of breathing at rest, during exercise and sleep. Pulmonary hypertension and respiratory failure may develop in severe disease. In this review the epidemiological and anatomical aspects of idiopathic scoliosis are noted, the pathophysiology and effects of idiopathic scoliosis on respiratory function are described, the pulmonary function testing including lung volumes, respiratory flow rates and airway resistance, chest wall movements, regional ventilation and perfusion, blood gases, response to exercise and sleep studies are presented. Preoperative pulmonary function testing required, as well as the effects of various surgical approaches on respiratory function are also discussed.