NMR of proteins and nucleic acids

NMR of proteins and nucleic acids
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DOI:
10.1002/chin.198812400
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发表时间:
1988-03
期刊:
--
影响因子:
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通讯作者:
K. Wüthrich
K. Wüthrich
中科院分区:
其他
文献类型:
--
作者:
K. Wüthrich

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引言和综述。基础:生物聚合物的结构和核磁共振。氨基酸残基和单核苷酸的核磁共振。蛋白质和核酸在溶液中的核磁共振波谱生物聚合物中的核磁共振分配问题。蛋白质和核酸的二维核磁共振。生物聚合物中的核增强(NOE)。蛋白质的共振指认和结构测定。蛋白质中不可见的1H-1H距离。蛋白质中的序列特异性共振指定。核磁共振研究蛋白质中的多肽二级结构。用核磁共振技术研究蛋白质的三维结构。核酸的共振归属与结构测定核酸中不可见的1H-1H距离。用标量耦合对核酸中的共振进行归属。核酸构象,1H-1H Overhaser效应,和序列特异性共振指定。随着核磁共振的发展,生物聚合物的构象和更高的构象。非晶态蛋白质和核酸的构象。生物聚合物分子间相互作用的核磁共振研究。参考资料。索引。
Introduction and Survey. THE FOUNDATIONS: STRUCTURE AND NMR OF BIOPOLYMERS. NMR of Amino Acid Residues and Mononucleotides. NMR Spectra of Proteins and Nucleic Acids in Solution. The NMR Assignment Problem in Biopolymers. Two-Dimensional NMR With Proteins and Nucleic Acids. Nuclear Overhauser Enhancement (NOE) in Biopolymers. RESONANCE ASSIGNMENTS AND STRUCTURE DETERMINATION IN PROTEINS. NOE-Observable 1H-1H Distances in Proteins. Sequence-Specific Resonance Assignments in Proteins. Polypeptide Secondary Structures in Proteins by NMR. Three-Dimensional Protein Structures by NMR. RESONANCE ASSIGNMENTS AND STRUCTURE DETERMINATION IN NUCLEIC ACIDS. NOE-Observable 1H-1H Distances in Nucleic Acids. Resonance Assignments in Nucleic Acids Using Scalar Couplings. Nucleic Acid Conformation, 1H-1H Overhauser Effects, and Sequence-Specific Resonance Assignments. WITH NMR TO BIOPOLYMER CONFORMATION AND BEYOND. Conformation of Noncrystalline Proteins and Nucleic Acids. NMR Studies of Intermolecular Interactions with Biopolymers. References. Index.