Data of cytotoxicity, p53 and Akt downstream proteins and physiological indexes in hepatocellular carcinoma cells or HepG2-bearing nude mouse model administered by α-Humulene
Data of cytotoxicity, p53 and Akt downstream proteins and physiological indexes in hepatocellular carcinoma cells or HepG2-bearing nude mouse model administered by α-Humulene
复制标题
α-Humulene对肝癌细胞或HepG2裸鼠模型的细胞毒性、p53和Akt下游蛋白及生理指标数据
DOI:
10.1016/j.dib.2020.105325
复制
发表时间:
2020-02
期刊:
影响因子:
1.2
通讯作者:
Xinzhou Yang
中科院分区:
文献类型:
--
作者:
Hao Chen;Ji Hao;Yanzhang Wen;Yibing Lv;Lu Chen;Jingquan Yuan;Xinzhou Yang
This data article contains data related to the research article entitled “α-Humulene inhibits hepatocellular carcinoma (HCC) cell proliferation and induces apoptosis through the inhibition of Akt signaling” (Chen et al., 2019) [1]. The article focuses on the antiproliferation of α-Humulene (HML) and the mechanisms involved in HCC cells inhibition. In this data, cytotoxicity of HML in several HCC cell lines are reported, together with the changes in proteins involving in p53 and Akt downstream. Weight curve, blood biochemical parameters and organ indices from HepG2-bearing nude mouse model are also provided, suggesting the potential side effects in HML administration.
登录
查看更多内容
影响因子:
5.7
作者:
Ma Y;Hao S;Wang S;Zhao Y;Lim B;Lei M;Spector DJ;El-Deiry WS;Zheng SY;Zhu J
通讯作者:
Zhu J
影响因子:
4.4
作者:
Zhang Y;Zhang Y;Yu Y
通讯作者:
Yu Y
DOI:
10.1016/j.fct.2010.08.017
发表时间:
2011
期刊:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
影响因子:
--
作者:
C. Su;Fang-Nan Chen;S. Won
通讯作者:
C. Su;Fang-Nan Chen;S. Won
影响因子:
4.3
作者:
Chen, Hao;Yuan, Jingquan;Yang, Xinzhou
通讯作者:
Yang, Xinzhou