SEROTONERGIC INFLUENCES ON THE SOCIAL-BEHAVIOR OF VERVET MONKEYS (CERCOPITHECUS-AETHIOPS-SABAEUS)
SEROTONERGIC INFLUENCES ON THE SOCIAL-BEHAVIOR OF VERVET MONKEYS (CERCOPITHECUS-AETHIOPS-SABAEUS)
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DOI：
10.1016/0014-4886(80)90089-8
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发表时间：
1980-01-01
影响因子：
5.3
通讯作者：
GELLER, E
中科院分区：
文献类型：
--
作者：
RALEIGH, MJ;BRAMMER, GL;GELLER, E
The behavioral effects of altering serotonin neurotransmission by chronic drug treatments in socially living vervet monkeys were examined. Animals received tryptophan (TRP, 20 mg/kg per day), p-chlorophenylalanine (PCPA, 80 mg/kg per day), 5-hydroxytryptophan (5-HTP, 40 mg/kg per day), chlorgyline (10 mg/kg per day), or PCPA followed by concurrent PCPA and 5-HTP. Grooming, approaching, resting and eating were increased by TRP and decreased by PCPA, TRP decreased and PCPA increased locomoting, avoiding, being solitary and being vigilant. Grooming, being vigilant and receiving aggression were increased by 5-HTP, and PCPA increased initiating aggression and decreased huddling. Concurrent administration of 5-HTP and PCPA reversed the effects of PCPA on approaching, grooming and resting; augmented the PCPA effects on avoiding, being solitary and aggression; and did not alter the PCPA effects on eating, locomoting and huddling. Chlorgyline increased grooming, approaching and being vigilant and decreased being solitary. No treatment significantly affected sexual behavior. Serotonergic systems contribute relatively substantially to the mediation of grooming and approaching, participate less strongly in resting and locomoting, are implicated still more weakly in being solitary, avoiding and being vigilant, and have little if any involvement in huddling, aggression and sexual behavior.
