Safety Measurements for Heating of Instruments for Cardiovascular Interventions in Magnetic Particle Imaging (MPI) - First Experiences

Safety Measurements for Heating of Instruments for Cardiovascular Interventions in Magnetic Particle Imaging (MPI) - First Experiences
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DOI:
10.1260/2040-2295.5.1.79
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发表时间:
2014-03-01
影响因子:
--
通讯作者:
Vogt, Florian M.
Vogt, Florian M.
中科院分区:
医学4区
文献类型:
--
作者:
Duschka, Robert L.;Wojtczyk, Hanne;Vogt, Florian M.

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磁粒子成像 (MPI) 已成为一种新的成像方法,具有提供高空间和时间分辨率且无电离辐射的图像的潜力。最近的研究证明了磁粒子光谱 (MPS) 中信号生成和非信号生成设备的区分以及 MPI 本身中商用导管和导丝的可视化的可行性。因此,MPI 似乎是一种有前途的心血管干预成像工具。本研究对几种市售导管和导丝进行了有关加热的测试。加热行为与设备生成并由 MPI 测量的光谱相关。结果表明,由于信号生成仪器的测量温度变化范围很广,因此应单独测试每台仪器,与非信号生成设备相比,温度变化高达 85 摄氏度。更高的温度似乎限制了这些设备在心血管干预中的使用。
Magnetic particle imaging (MPI) has emerged as a new imaging method with the potential of delivering images of high spatial and temporal resolutions and free of ionizing radiation. Recent studies demonstrated the feasibility of differentiation between signal-generating and non-signal-generating devices in Magnetic Particle Spectroscopy (MPS) and visualization of commercially available catheters and guide-wires in MPI itself. Thus, MPI seems to be a promising imaging tool for cardiovascular interventions. Several commercially available catheters and guide-wires were tested in this study regarding heating. Heating behavior was correlated to the spectra generated by the devices and measured by the MPI. The results indicate that each instrument should be tested separately due to the wide spectrum of measured temperature changes of signal-generating instruments, which is up to 85 degrees C in contrast to non-signal-generating devices. Development of higher temperatures seems to be a limitation for the use of these devices in cardiovascular interventions.