Laparoscopic versus open liver resection for hepatocellular carcinoma: Case-matched study with propensity score matching
Laparoscopic versus open liver resection for hepatocellular carcinoma: Case-matched study with propensity score matching
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DOI：
10.1016/j.jhep.2015.04.005
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发表时间：
2015-09-01
影响因子：
25.7
通讯作者：
Choi, YoungRok
中科院分区：
文献类型：
--
作者：
Han, Ho-Seong;Shehta, Ahmed;Choi, YoungRok
背景和目的：腹腔镜肝切除术已获得广泛接受，并被确立为开腹肝切除术的安全替代方案。迄今为止，尚无腹腔镜与开腹肝切除术之间的前瞻性随机比较研究。之前的比较研究报告了对周围肿瘤的小切除术，并招募了少量患者。此外，很少有人报告长期结果。本研究的目的是比较两个匹配组之间腹腔镜与开腹肝切除术治疗肝细胞癌的围手术期和长期结果。方法：2004 年至 2013 年间，389 名患者接受了肝细胞癌肝切除术。为了克服选择偏倚，我们使用腹腔镜和开腹肝切除术之间的倾向评分匹配进行 1:1 匹配。结果：倾向评分匹配后，纳入了 88 名患者在每个组中。腹腔镜组住院时间较短（8 天 vs. 10 天，p）
Background & Aims: Laparoscopic liver resection has gained wide acceptance and is established as a safe alternative to open liver resection. Until now, there is no prospective randomized comparative study between laparoscopic and open liver resection. Previous comparative studies reported minor resections for peripheral tumors, and enrolled small numbers of patients. Moreover, few reported the long term outcomes. The aim of this study is to compare perioperative and long term outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma between two matched groups.Methods: 389 patients underwent liver resection for hepatocellular carcinoma during the period between 2004 and 2013. To overcome selection bias, we performed 1:1 match using propensity score matching between laparoscopic and open liver resection.Results: After propensity score matching, 88 patients were included in each group. Laparoscopic group had shorter hospital stay (8 vs. 10 days, p