OSTEOMYELITIS IN THE FEET OF DIABETIC-PATIENTS - LONG-TERM RESULTS, PROGNOSTIC FACTORS, AND THE ROLE OF ANTIMICROBIAL AND SURGICAL THERAPY
OSTEOMYELITIS IN THE FEET OF DIABETIC-PATIENTS - LONG-TERM RESULTS, PROGNOSTIC FACTORS, AND THE ROLE OF ANTIMICROBIAL AND SURGICAL THERAPY
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DOI：
10.1016/0002-9343(87)90894-1
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发表时间：
1987-10-01
影响因子：
5.9
通讯作者：
GERDING, DN
中科院分区：
文献类型：
--
作者：
BAMBERGER, DM;DAUS, GP;GERDING, DN
Fifty-one diabetic patients with osteomyelitis of the foot were studied to determine potential prognostic factors and the role of antimicrobial therapy. Most of the patients were elderly, with diminished pulses, a sensory neuropathy, and apolymicrobial infection. Twenty-seven patients had a good outcome, defined as clinical resolution at the time of the last follow-up examination, without the need for amputation. The mean duration of follow-up for these patients was 19 months. Fifteen patients had a below-knee amputation, and nine had a toe amputation. The absence of necrosis and/or gangrene, the presence of swelling, and the use of antimicrobial therapy active against the isolated pathogens for at least four weeks intravenously, or combined intravenously and orally for 10 weeks, predicted a good outcome. Diabetic foot osteomyelitis, in the absence of extensive necrosis or gangrene, usually responds to antimicrobial therapy without the need for an ablative surgical procedure.
