Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status A Randomized Clinical Trial

Fresh Red Blood Cell Transfusion and Short-Term Pulmonary, Immunologic, and Coagulation Status A Randomized Clinical Trial
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DOI:
10.1164/rccm.201107-1332oc
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发表时间:
2012-04-15
影响因子:
24.7
通讯作者:
Gajic, Ognjen
Gajic, Ognjen
中科院分区:
医学1区
文献类型:
--
作者:
Kor, Daryl J.;Kashyap, Rahul;Gajic, Ognjen

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Rationale: Transfusion-related pulmonary complications are leading causes of morbidity and mortality attributed to transfusion. Observational studies suggest an important role for red blood cell (RBC) storage duration in these adverse outcomes.Objectives: To evaluate the impact of RBC storage duration on short-term pulmonary function as well as immunologic and coagulation status in mechanically ventilated patients receiving RBC transfusion.Methods: This is a double-blind, randomized, clinical trial comparing fresh (