Molecular Imaging of Atherosclerosis: A Clinical Focus.
Molecular Imaging of Atherosclerosis: A Clinical Focus.
复制标题
动脉粥样硬化的分子成像：临床焦点。
DOI：
10.1007/s12410-017-9397-1
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发表时间：
2017
影响因子：
0.9
通讯作者：
Jaffer,FaroucA
中科院分区：
文献类型：
--
作者：
Chowdhury,MohammedM;Tawakol,Ahmed;Jaffer,FaroucA
综述目的心血管疾病的分子成像是一种强有力的临床和实验方法，可以为我们了解动脉粥样硬化生物学提供信息。分子成像技术可以提供详细的解剖学信息，补充横断面成像技术，可以进一步检测动脉粥样硬化内发生的重要生物学变化，并改善血管并发症的预测。Recent FindingsMolecular imaging of atherosclerosis can illuminate underlying pathophysiology and serve as a surrogate endpoint in clinical trials of new drugs.SummaryThis review showcrossed pronounced molecular approaches for imaging atherosclerosis，重点是临床或接近临床使用的正电子发射断层扫描（PET）、磁共振成像（MRI）和血管内近红外荧光（NIRF）成像方法。
Purpose of ReviewMolecular imaging of cardiovascular disease is a powerful clinical and experimental approach that can inform our understanding of atherosclerosis biology. Complementing cross-sectional imaging techniques that provide detailed anatomical information, molecular imaging can further detect important biological changes occurring within atheroma and refine the prediction of vascular complications.Recent FindingsMolecular imaging of atherosclerosis can illuminate underlying pathophysiology and serve as a surrogate endpoint in clinical trials of new drugs.SummaryThis review showcases promising molecular approaches for imaging atherosclerosis, with a focus on positron emission tomography (PET), magnetic resonance imaging (MRI), and intravascular near-infrared fluorescence (NIRF) imaging methods that are in the clinic or close-to-clinical usage.