Returning HIV-1 viral load results to participant-selected health facilities in national Population-based HIV Impact Assessment (PHIA) household surveys in three sub-Saharan African Countries, 2015 to 2016.
Returning HIV-1 viral load results to participant-selected health facilities in national Population-based HIV Impact Assessment (PHIA) household surveys in three sub-Saharan African Countries, 2015 to 2016.
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DOI：
10.1002/jia2.25004
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发表时间：
2017-11
影响因子：
6
通讯作者：
Voetsch AC
中科院分区：
文献类型：
--
作者：
Saito S;Duong YT;Metz M;Lee K;Patel H;Sleeman K;Manjengwa J;Ogollah FM;Kasongo W;Mitchell R;Mugurungi O;Chimbwandira F;Moyo C;Maliwa V;Mtengo H;Nkumbula T;Ndongmo CB;Vere NS;Chipungu G;Parekh BS;Justman J;Voetsch AC
将实验室检测结果返回给参与者的逻辑复杂性使得在撒哈拉以南非洲进行的大多数基于人口的艾滋病毒调查无法这样做。对于艾滋病毒阳性的参与者来说，这意味着错过了参与临床护理和改善健康结果的机会。基于人口的艾滋病毒影响评估（PHIA）调查衡量了选定非洲国家的艾滋病毒发病率和病毒载量（VL）抑制的流行程度，在收集后八周内将VL结果返回给每个艾滋病毒阳性参与者指定的卫生机构。我们描述了用于返回VL结果PHIA参与者在津巴布韦，马拉维和赞比亚的标本和数据管理系统的性能。根据国家检测指南，确诊的受试者接受了家庭咨询和HIV快速检测;所有确诊的HIV阳性受试者均在中心实验室使用Roche CAP/CTM或Abbott m2000平台测量了VL。每两周，一个专门的数据管理团队制作日志，将VL测试结果与参与者的联系信息和首选医疗机构联系起来;项目工作人员通过项目驱动程序、国家快递系统或通过适配的短信服务（SMS）以电子方式保密发送测试结果。提供手机号码的参与者会收到关于VL结果可用性的短信或电话提醒。在这三个国家的29，634个家庭中，津巴布韦和马拉维的78，090名0至64岁的参与者以及赞比亚的0至59岁的参与者接受了抽血和艾滋病毒检测。在确定的8391名艾滋病毒阳性参与者中，有8313人（99%）进行了VL检测，其中8245人（99%）被送回选定的卫生设施。在津巴布韦和赞比亚返回的5979个VL结果中，85%在8周目标内返回，中位周转时间为48天（IQR：33至61）。在马拉维，没有确切的返回日期，所有2 266份应返回的结果在11周内到达卫生设施。前三次PHIA调查在八周的目标内将绝大多数VL结果返回给每个HIV阳性参与者的首选医疗机构。即使没有国家VL监测系统，从基于人口的调查中返回VL结果的系统也是可行的，但它需要开发实验室和数据管理系统以及专门的工作人员。这些可能是加强常规临床护理结果返回系统的重要要求。
Logistical complexities of returning laboratory test results to participants have precluded most population‐based HIV surveys conducted in sub‐Saharan Africa from doing so. For HIV positive participants, this presents a missed opportunity for engagement into clinical care and improvement in health outcomes. The Population‐based HIV Impact Assessment (PHIA) surveys, which measure HIV incidence and the prevalence of viral load (VL) suppression in selected African countries, are returning VL results to health facilities specified by each HIV positive participant within eight weeks of collection. We describe the performance of the specimen and data management systems used to return VL results to PHIA participants in Zimbabwe, Malawi and Zambia. Consenting participants underwent home‐based counseling and HIV rapid testing as per national testing guidelines; all confirmed HIV positive participants had VL measured at a central laboratory on either the Roche CAP/CTM or Abbott m2000 platform. On a bi‐weekly basis, a dedicated data management team produced logs linking the VL test result with the participants’ contact information and preferred health facility; project staff sent test results confidentially via project drivers, national courier systems, or electronically through an adapted short message service (SMS). Participants who provided cell phone numbers received SMS or phone call alerts regarding availability of VL results. From 29,634 households across the three countries, 78,090 total participants 0 to 64 years in Zimbabwe and Malawi and 0 to 59 years in Zambia underwent blood draw and HIV testing. Of the 8391 total HIV positive participants identified, 8313 (99%) had VL tests performed and 8245 (99%) of these were returned to the selected health facilities. Of the 5979 VL results returned in Zimbabwe and Zambia, 85% were returned within the eight‐week goal with a median turnaround time of 48 days (IQR: 33 to 61). In Malawi, where exact return dates were unavailable all 2266 returnable results reached the health facilities by 11 weeks. The first three PHIA surveys returned the vast majority of VL results to each HIV positive participant's preferred health facility within the eight‐week target. Even in the absence of national VL monitoring systems, a system to return VL results from a population‐based survey is feasible, but it requires developing laboratory and data management systems and dedicated staff. These are likely important requirements to strengthen return of results systems in routine clinical care.
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影响因子：
3.7
作者：
Rutstein SE;Hosseinipour MC;Kamwendo D;Soko A;Mkandawire M;Biddle AK;Miller WC;Weinberger M;Wheeler SB;Sarr A;Gupta S;Chimbwandira F;Mwenda R;Kamiza S;Hoffman I;Mataya R
通讯作者：
Mataya R
影响因子：
3.8
作者：
Lofgren, Sarah M.;Morrissey, Anne B.;Crump, John A.
通讯作者：
Crump, John A.
艾滋病毒护理连续体中的人员流失和机会：来自南非西北省人口样本的调查结果。
DOI：
10.1097/qai.0000000000001026
发表时间：
2016-09-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Lippman SA;Shade SB;El Ayadi AM;Gilvydis JM;Grignon JS;Liegler T;Morris J;Naidoo E;Prach LM;Puren A;Barnhart S
通讯作者：
Barnhart S
影响因子：
4.1
作者：
Field, Nigel;Tanton, Clare;Sonnenberg, Pam
通讯作者：
Sonnenberg, Pam
影响因子：
3.8
作者：
Floyd, Sian;Molesworth, Anna;Glynn, Judith R.
通讯作者：
Glynn, Judith R.