Influence of temperature, [Ca2+], Ca/P ratio and ultrasonic power on the crystallinity and morphology of hydroxyapatite nanoparticles prepared with a novel ultrasonic precipitation method
Influence of temperature, [Ca2+], Ca/P ratio and ultrasonic power on the crystallinity and morphology of hydroxyapatite nanoparticles prepared with a novel ultrasonic precipitation method
复制标题
DOI：
10.1016/j.matlet.2005.02.007
复制
发表时间：
2005-06-01
影响因子：
3
通讯作者：
Huang, JF
中科院分区：
文献类型：
--
作者：
Cao, LY;Zhang, CB;Huang, JF
以Ca（NO3）2和NH 4 H2 PO 4为原料，尿素（NH 2CONH 2）为沉淀剂，采用超声辅助沉淀法制备纳米羟基磷灰石。通过XRD分析，系统研究了Ca/P摩尔比、沉淀温度、Ca 2+（[Ca 2 +]）浓度和超声功率对纳米粉体结晶度的影响。用TEM和XRD方法分析了所制备的颗粒的尺寸。结果表明，在[Ca 2 +]=0.01- 0.1mol/L，超声功率为300 W，Ca/P（mol）=1.2-2.5，温度为313-353 K的条件下，可以得到单相羟基磷灰石。此外，针状和球形粒子可以在不同的超声功率为300和200 W，分别制备。(c)2005 Elsevier B. V.保留所有权利。
Nanocrystalline hydroxyapatite was prepared by a precipitation method with the aid of ultrasonic irradiation using Ca(NO3)(2) and NH4H2PO4 as source material and carbamide (NH2CONH2) as precipitator. The influence of Ca/P molar ratio, precipitation temperature, concentration of Ca2+ ([Ca2+]) and ultrasonic power on the crystallinity of the nanopowder were systematically investigated by XRD analysis. The size of the as-prepared particles was analyzed using TEM and XRD methods. The results revealed that the monophase hydroxyapatite could be obtained at the following technological conditions: [Ca2+]=0.01-0.1 mol/L, ultrasonic power-300 W, Ca/P (mol)=1.2-2.5 and T=313-353 K. In addition, the acicular and spherical particles could be prepared at different ultrasonic powers of 300 and 200 W, respectively. (c) 2005 Elsevier B.V. All rights reserved.