A qualitative assessment of randomized controlled trials in otolaryngology
A qualitative assessment of randomized controlled trials in otolaryngology
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DOI：
10.1017/s0022215100140770
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发表时间：
1998-05-01
影响因子：
1.7
通讯作者：
Molony, NC
中科院分区：
文献类型：
--
作者：
Ah-See, KW;Molony, NC
1996年，CONSORT声明建议严格报告随机对照试验（RCT）。这将有助于未来对此类试验的评估，并将突出那些进行得不理想且结果可能有偏差的试验。我们设计了一个评分系统，基于CONSORT，通过阅读每篇原始文献，我们评估了1966年至1995年发表的临床试验的质量。12分。没有一本杂志明显优于其他杂志。据报道，肿瘤学试验优于头颈部肿瘤学试验（平均得分分别为7.6和6.5）。在过去的30年里，临床试验的质量并没有得到提高，耳鼻喉科文献中的随机对照试验报道也很少。CONSORT指南现在已经存在，并鼓励试验者在进行未来的临床试验时采用这些指南。
In 1996 the CONSORT statement made recommendations on the strict reporting of randomized controlled trials (RCT). This will facilitate the future assessment of such trials and will highlight those trials that have been performed suboptimally and whose results may be biased.We have devised a scoring system, based on CONSORT, to assess RCT quality and by reading each original paper in full we have now assessed the quality of trials published from 1966 to 1995.The mean score for trials identified was 7.3 out of a maximum 12 points. No one journal was significantly better than the others. Trials in rhinology are reported better than head and neck oncology trials (mean scores 7.6 and 6.5 respectively). The past 30 years has not seen an improvement in the quality of the trials.The reporting of RCTs in the ENT literature is poor. CONSORT guidelines now exist and trialists are encouraged to adopt them when conducting future clinical trials.