Investigation of human cervical and upper thoracic spinal cord motion: Implications for imaging spinal cord structure and function
Investigation of human cervical and upper thoracic spinal cord motion: Implications for imaging spinal cord structure and function
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DOI：
10.1002/mrm.21260
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发表时间：
2007-07-01
影响因子：
3.3
通讯作者：
Stroman, P. W.
中科院分区：
文献类型：
--
作者：
Figley, C. R.;Stroman, P. W.
脊髓(SC)运动被认为是当前弥散成像和脊髓功能磁共振成像(FMRI)方法的主要误差来源。然而，到目前为止，这种运动在三个维度上还没有得到很好的描述。虽然以前的研究主要研究上/下(S/I)方向的运动，但本研究的焦点是人颈和上胸椎SC运动的前/后(A/P)和右/左(R/L)分量。心脏门控、TurboFAST低角度拍摄(Turbo-Flash)电影MRI在3T使用，以获取整个心脏周期24个时相的脐带图像。然后使用邻近脊髓/脑脊液(CSF)界面的体素内随时间变化的信号波动来测量SC运动，这被发现是作为心脏活动的函数而发生的。脐带在A/P方向的运动是最大的，计算了运动的主要分量，从而表明SC振荡的一致模式可能被用于改善SC成像。《医学评论》58：185-189,2007。(C)2007年Wiley-Liss，Inc.
Spinal cord (SC) motion is thought to be the dominant source of error in current diffusion and spinal functional MRI (fMRI) methods. However, until now, such motion has not been well characterized in three dimensions. While previous studies have predominantly examined motion in the superior/inferior (S/I) direction, the foci of the present study were the anterior/posterior (A/P) and right/left (R/L) components of human cervical and upper thoracic SC motion. Cardiac-gated, turbofast low-angle shot (turbo-FLASH) cinematic MRI was employed at 3T to acquire images of the cord at 24 phases throughout the cardiac cycle. Time-dependent signal fluctuations within voxels adjacent to the cord/cerebrospinal fluid (CSF) interface were then used to measure SC motion, which was found to occur predictably as a function of cardiac activity. Cord movement was largest in the A/P direction, for which principal components of motion were calculated, thereby indicating consistent patterns of SC oscillation that can potentially be used to improve SC imaging. Magn Reson Med 58:185-189, 2007. (c) 2007 Wiley-Liss, Inc.