Serum advanced glycation end products (AGEs) are associated with insulin resistance

Serum advanced glycation end products (AGEs) are associated with insulin resistance
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DOI：
10.1002/dmrr.1188
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发表时间：
2011-07
期刊：
Diabetes/Metabolism Research and Reviews
影响因子：
--
通讯作者：
K. Tan;S. M. Shiu;Y. Wong;X. Tam
K. Tan;S. M. Shiu;Y. Wong;X. Tam
中科院分区：
其他
文献类型：
--
作者：
K. Tan;S. M. Shiu;Y. Wong;X. Tam

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除了晚期糖基化终末产物（AGEs）在糖尿病血管并发症发病机制中的重要作用外，最近的数据表明，晚期糖基化终末产物也可在体外损害胰岛素作用。我们研究了循环晚期糖基化终产物是否与人体胰岛素抵抗相关，而与代谢参数无关。
In addition to the important role of advanced glycation end products (AGEs) in the pathogenesis of diabetic vascular complications, recent data suggest that advanced glycation end products can also impair insulin action in vitro. We have investigated whether circulating advanced glycation end products are associated with insulin resistance in human subjects independent of metabolic parameters.