LDL-cholesterol and insulin are independently associated with body mass index in adult cystic fibrosis patients
LDL-cholesterol and insulin are independently associated with body mass index in adult cystic fibrosis patients
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DOI：
10.1016/j.jcf.2012.03.006
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发表时间：
2012-09-01
影响因子：
5.2
通讯作者：
Rabasa-Lhoret, Remi
中科院分区：
文献类型：
--
作者：
Coderre, Lise;Fadainia, Christophe;Rabasa-Lhoret, Remi
Background: The median life expectancy of cystic fibrosis (CF) patients has increased dramatically over the last few years and we now observe a subset of patients with a body mass index (BMI) exceeding 25 kg/m(2). The aim of this study was to characterize these individuals and to identify factors associated with higher BMI.Methods: This is a cross sectional study including 187 adult CF subjects. Percent predicted forced expiratory volume in 1 s (%FEV1), blood lipid profiles as well as fasting glucose and insulin levels were evaluated. Subjects also had an oral glucose tolerance test (OGTT) and the area under the curve (AUC) for glucose and insulin was calculated. CF subjects were then stratified according to the following BMI categories: underweight: BMI
