The Gait Disorientation Test: A New Method for Screening Adults With Dizziness and Imbalance.

The Gait Disorientation Test: A New Method for Screening Adults With Dizziness and Imbalance.
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DOI:
10.1016/j.apmr.2020.11.010
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发表时间:
2021-04
影响因子:
4.3
通讯作者:
Whitney SL
Whitney SL
中科院分区:
医学1区
文献类型:
--
作者:
Grove CR;Heiderscheit BC;Pyle GM;Loyd BJ;Whitney SL

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开发和评估一种识别前庭功能障碍所致步态迷失的新方法。步态迷失测试 (GDT) 包括对睁眼与闭眼行走 6.096 m 的能力进行定时比较。在这项前瞻性研究中,参与者根据前庭功能进行分组。所有参与者均完成了临床检查、与前庭康复相关的自我报告和基于表现的测量以及 GDT 的任务。前庭受损的参与者接受了标准、视频眼震图和/或旋转椅测试。门诊诊所、三级转诊中心。参与者 (N=40)(20 名前庭受损患者、30 名女性、49.9±16.1 岁)是从 52 名成年人的便利/转介样本中招募的。我们使用组内相关系数模型 3,1 确定重测信度;计算最小可检测变化(MDC);通过斯皮尔曼相关系数检查同时有效性;通过受试者操作者特征分析的曲线下面积 (AUC) 评估标准有效性;并计算了敏感性、特异性、诊断比值比 (DOR)、阳性 (LR+) 和阴性 (LR−) 测试的似然比以及诊断前庭病的测试后概率。 95% 置信区间表明了测量的不确定性。重测信度为 0.887 (0.815, 0.932)。 MDC 为 3.7 秒。与其他指标的相关性范围为 0.59 (0.34, 0.76) 至 -0.85 (-0.92, -0.74)。使用 4.5 秒的阈值时,AUC 为 0.910 (0.822, 0.998)。敏感性和特异性分别为 0.75 (0.51, 0.91) 和 0.95 (0.75, 1)。 DOR=57 (6, 541.47),LR+ =15 (2.18, 103.0),LR− =0.26 (0.12, 0.9)。测试后阳性概率为 89%–94%。 GDT具有良好的信度、优异的判别能力、较强的收敛效度和良好的临床应用前景。
To develop and evaluate a new method for identifying gait disorientation due to vestibular dysfunction. The gait disorientation test (GDT) involves a timed comparison of the ability to walk 6.096 m with eyes open versus eyes closed. In this prospective study, participants were grouped based on vestibular function. All participants completed a clinical examination, self-report- and performance-based measures relevant to vestibular rehabilitation, and the tasks for the GDT. Vestibular-impaired participants underwent the criterion standard, videonystagmography and/or rotational chair testing. Ambulatory clinic, tertiary referral center. Participants (N=40) (20 vestibular-impaired, 30 women, 49.9±16.1years old) were enrolled from a convenience/referral sample of 52 adults. We determined test-retest reliability using the intraclass correlation coefficient model 3,1; calculated the minimal detectable change (MDC); examined concurrent validity through Spearman correlation coefficients; assessed criterion validity with the area under the curve (AUC) from receiver operator characteristic analysis; and computed the sensitivity, specificity, diagnostic odds ratio (DOR), likelihood ratios for positive (LR+) and negative (LR−) tests, and posttest probabilities of a diagnosis of vestibulopathy. The 95% confidence interval demonstrates measurement uncertainty. Test-retest reliability was 0.887 (0.815, 0.932). The MDC was 3.7 seconds. Correlations with other measures ranged from 0.59 (0.34, 0.76) to −0.85 (−0.92, −0.74). The AUC was 0.910 (0.822, 0.998), using a threshold of 4.5 seconds. The sensitivity and specificity were 0.75 (0.51, 0.91) and 0.95 (0.75, 1), respectively. The DOR=57 (6, 541.47), LR+ =15 (2.18, 103.0), and LR− =0.26 (0.12, 0.9). Positive posttest probabilities were 89%–94%. The GDT has good reliability, excellent discriminative ability, strong convergent validity, and promising clinical utility.
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