Evaluation of adaptogenic and anti-stress effects of Ranahamsa Rasayanaya-A Sri Lankan classical Rasayana drug on experimental animals.
Evaluation of adaptogenic and anti-stress effects of Ranahamsa Rasayanaya-A Sri Lankan classical Rasayana drug on experimental animals.
复制标题
DOI：
10.4103/0974-8520.68201
复制
发表时间：
2010-01
期刊：
影响因子：
--
通讯作者：
Ashok BK
中科院分区：
文献类型：
--
作者：
Somarathna KI;Chandola HM;Ravishankar B;Pandya KN;Attanayake AM;Ashok BK
各种各样的压力不仅损害精神功能，而且还会削弱身体的防御能力，从而导致疾病。在这种情况下，Rasayana疗法比传统的Kayachikitsa疗法有优势，因为它能够抵消压力，促进身体的适应能力，增强精神耐力等。这些是评价药物的rasayana效果的一些参数，因此研究了Ranahamsa Rasayanaya （RR）的rasayana效果。采用适合Charles Foster品系白化病大鼠的强迫游泳诱导低体温、应激诱导胃溃疡形成等实验模型来确定RR的rasayana效果。与应激对照组相比，治疗组强迫游泳引起的体温过低发生率显著降低，胃溃疡形成发生率无显著降低。这些结果表明，试验药物可能具有适应原性和抗应激活性。研究结果支持了斯里兰卡传统从业者的说法，即测试药物是一种有效的rasayana配方。
Various types of stress not only harm the mental function, but also cause diseases by weakening body defenses. Rasayana therapy has an advantage over the conventional Kayachikitsa treatment in such conditions, as it is capable of counteracting the stress, promote the adaptogenic abilities of the body, enhance mental endurance, etc. These are the some of parameters for evaluation the rasayana effect of a drug, therefore the same have been studied to assess the rasayana effect of Ranahamsa Rasayanaya (RR). Experimental models such as forced swimming induced hypothermia and stress induced gastric ulcer formation have been carried out befitting on Charles Foster strain albino rats to determine the rasayana effect of RR. Statistically highly significant decrease in forced swimming induced hypothermia and non-significant decrease in gastric ulcer formation were observed in the treatment groups, when compared to the stress control group. These results show the probable adaptogenic and anti-stress activities of the test drug. The study results support the claims made by the Sri Lankan traditional practitioners that, the test drug is a potent rasayana formulation.