A reclassification of B and C neurones in the ninth and tenth paravertebral sympathetic ganglia of the bullfrog.
A reclassification of B and C neurones in the ninth and tenth paravertebral sympathetic ganglia of the bullfrog.
复制标题
牛蛙第九和第十椎旁交感神经节 B 和 C 神经元的重新分类。
DOI：
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
J. Horn
中科院分区：
文献类型：
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作者：
J. Dodd;J. Horn
1.用细胞内和细胞外记录方法研究了牛蛙第九和第十椎旁交感神经节的细胞结构。使用了一种隔离的制剂，其中可以在进行生理测量的同时解析单个细胞的解剖细节。这使得可以根据神经元的大小、其胆碱能神经的节段性来源以及它们的顺向和反向传导速度来表征神经元。根据这些标准，我们识别出三类交感神经元。2.与以往的研究一样，C细胞和B细胞的神经来源不同。C细胞由脊神经7、8的慢传导性轴突(0.4m/s)支配，B细胞由7.3节以上交感神经链的快速传导性轴突(2.4m/s)支配。早期的研究表明节前轴突的传导速度与其靶神经元的传导速度基本一致。在这项研究中，我们描述了一大群B细胞，但事实并非如此。B细胞轴突分为快速传导组(2.0m/s)和慢传导组(0.6m/s)。相比之下，C神经元，就像它们的节前输入一样，只有缓慢传导的轴突(0.3米/秒)。因此，神经元被分为C型、快B型和慢B型。我们研究的B细胞中有59%是慢B细胞。节后神经的复合细胞外反应的测量证实了这些发现。4.一些神经元也可以根据其胞体的大小进行识别。C细胞直径约30微米，而B细胞直径约50微米。在我们的样本中，半径小于16微米的细胞中96%是C细胞，半径大于21微米的细胞中94%是B细胞。然而，快B细胞和慢B细胞不能从大小上区分开来。
1. The cellular organization of the ninth and tenth paravertebral sympathetic ganglia in the bullfrog was studied with intracellular and extracellular recording methods. An isolated preparation was used in which anatomical details of individual cells could be resolved while making physiological measurements. This permitted the characterization of neurones in terms of their size, the segmental origin of their cholinergic innervation, and their orthodromic and antidromic conduction velocities. With these criteria, three classes of sympathetic neurones were identified. 2. As in previous studies, C cells were distinguished from B cells by the origin of their innervation. C cells are innervated by slowly conducting axons (0.4 m/sec) from spinal nerves 7 and 8 and B cells are innervated by rapidly conducting axons (2.4 m/sec) from the sympathetic chain above ganglion 7. 3. In earlier work it has been suggested that the conduction velocity of a preganglionic axon generally matches that of its target neurone. In this study we have characterized a large group of B cells for which this is not true. The axons of B cells fall into a rapidly conducting group (2.0 m/sec) and a slowly conducting group (0.6 m/sec). In contrast, C neurones, like their preganglionic inputs, have only slowly conducting axons (0.3 m/sec). Consequently, neurones have been classified as C type, fast B type, and slow B type. Fifty‐nine percent of the B cells that we studied were slow B cells. These findings were corroborated by measurements of compound extracellular responses in post‐ganglionic nerves. 4. Some neurones can be identified also by the size of their cell bodies. C cells are about 30 microns in diameter while B cells are about 50 microns in diameter. In our sample, 96% of the cells with radius less than 16 microns were C cells and 94% of the cells with radius greater than 21 microns were B cells. However, fast B cells could not be distinguished from slow B cells by size.
神经释放的递质快速激活突触前烟碱乙酰胆碱受体。
DOI：
10.1111/j.1460-9568.2003.03064.x
发表时间：
2003
期刊：
The European journal of neuroscience
影响因子：
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作者：
Rogers,Marc;Sargent,PeterB
通讯作者：
Sargent,PeterB