THE DISTRIBUTION OF MUSCULAR WEAKNESS IN UPPER MOTOR NEURON LESIONS AFFECTING THE ARM
THE DISTRIBUTION OF MUSCULAR WEAKNESS IN UPPER MOTOR NEURON LESIONS AFFECTING THE ARM
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DOI：
10.1093/brain/112.3.749
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发表时间：
1989-06-01
期刊：
影响因子：
14.5
通讯作者：
GANDEVIA, SC
中科院分区：
文献类型：
--
作者：
COLEBATCH, JG;GANDEVIA, SC
测量了12个肌肉群的手臂的力量，以确定上运动神经元无力在人类中的分布。三组受试者进行了研究：14个完整的志愿者（两侧记录），10例单侧手臂麻痹患者（两侧记录）和6例手臂严重瘫痪患者（仅测量“完整"手臂）。在对侧的致病性病变的无力模式是不一样的，在所有的患者。肩部肌肉相对不受影响，而腕屈肌和手指屈肌受到相对严重的影响，差异具有统计学意义。在偏瘫和偏瘫患者中，与正常对照组相比，病变同侧的肌肉力量降低。这些观察结果完善了以前的上运动神经元无力的临床描述，并对其病理生理学有影响。
The strength of 12 muscle groups of the arm was measured to determine the distribution of upper motor neuron weakness in man. Three groups of subjects were studied; 14 intact volunteers (both sides recorded), 10 patients with unilateral arm paresis (both sides recorded) and 6 patients with severe paralysis of the arm (the ''intact'' arm only measured). On the side contralateral to the causative lesion the pattern of weakness was not the same in all patients. Shoulder muscles were relatively spared while the wrist and finger flexors were relatively severely affected, the difference being statistically significant. In hemiparetic and hemiplegic patients the strength of muscles ipsilateral to the lesion was reduced compared with normal controls. These observations refine previous clinical descriptions of upper motor neuron weakness and have implications for its pathophysiology.