Sentence processing in anterior superior temporal cortex shows a social-emotional bias.
Sentence processing in anterior superior temporal cortex shows a social-emotional bias.
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DOI：
10.1016/j.neuropsychologia.2016.06.019
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发表时间：
2016-08
期刊：
影响因子：
2.6
通讯作者：
Martin A
中科院分区：
文献类型：
--
作者：
Mellem MS;Jasmin KM;Peng C;Martin A
左上级颞回/上级颞上沟（aSTG/STS）的前部区域参与两种非常不同的认知功能：句子加工和社会情绪加工。然而，绝大多数的句子刺激在以前的报告中已经社会或社会情感的性质表明，句子处理可能会混淆语义内容。为了评估这种可能性，我们让受试者在7 T环境中阅读不同短语/成分大小（单个单词，3个单词的短语，6个单词的句子）和语义内容（社会情感，社会和无生命物体）的单词列表。这使我们能够调查aSTG/STS是否对增加的组成结构（随着组成大小的增加而增加的活动）做出反应，而不管概念的特定领域，即，社交和/或社交情感内容。发现左侧aSTG/STS的活性随组分大小而增加。然而，这一区域也受到内容的调节，使得社会情感概念比社会和物体刺激更受欢迎。阅读也会在特定领域的语义区域产生内容类型效应。那些偏爱社会情感内容的人包括aSTG/STS、额下回、后STS、外侧梭状回、腹内侧前额叶皮层和杏仁核，这些区域包括“社会脑”，而那些偏爱物体内容的人包括海马旁回、压后皮层和尾状核，这些区域参与物体处理。这些结果表明，语义内容影响更高层次的语言处理，并应考虑在未来的研究。
The anterior region of the left superior temporal gyrus/superior temporal sulcus (aSTG/STS) has been implicated in two very different cognitive functions: sentence processing and social-emotional processing. However, the vast majority of the sentence stimuli in previous reports have been of a social or social-emotional nature suggesting that sentence processing may be confounded with semantic content. To evaluate this possibility we had subjects read word lists that differed in phrase/constituent size (single words, 3-word phrases, 6-word sentences) and semantic content (social-emotional, social, and inanimate objects) while scanned in a 7 T environment. This allowed us to investigate if the aSTG/STS responded to increasing constituent structure (with increased activity as a function of constituent size) with or without regard to a specific domain of concepts, i.e., social and/or social-emotional content. Activity in the left aSTG/STS was found to increase with constituent size. This region was also modulated by content, however, such that social-emotional concepts were preferred over social and object stimuli. Reading also induced content type effects in domain-specific semantic regions. Those preferring social-emotional content included aSTG/STS, inferior frontal gyrus, posterior STS, lateral fusiform, ventromedial prefrontal cortex, and amygdala, regions included in the “social brain”, while those preferring object content included parahippocampal gyrus, retrosplenial cortex, and caudate, regions involved in object processing. These results suggest that semantic content affects higher-level linguistic processing and should be taken into account in future studies.