Is comorbidity in adolescence a predictor for adult low back pain? A prospective study of a young population
Is comorbidity in adolescence a predictor for adult low back pain? A prospective study of a young population
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DOI：
10.1186/1471-2474-7-29
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发表时间：
2006-03-16
影响因子：
2.3
通讯作者：
Kyvik, KO
中科院分区：
文献类型：
--
作者：
Hestbaek, L;Leboeuf-Yde, C;Kyvik, KO
背景资料：以前已经表明，腰痛（LBP）通常在青少年时期就已经出现，并且以前的LBP预测未来的LBP。它也是有据可查的，有很大程度的合并症与LBP，无论是在青少年和成人。本研究的目的是更深入地了解腰痛的病因，并可能开发一种早期识别高危人群的工具。这是通过调查是否不同类型的发病率在青春期与LBP在adulty.Methods：近10,000丹麦双胞胎出生于1972年和1982年之间进行了调查，通过邮寄问卷在1994年和2002年再次。问卷涉及一般健康的各个方面，包括LBP的患病率，根据上一年受影响的天数（0，1 - 7，8 - 30，> 30）进行分类。本研究中使用的预测变量是基线时的LBP、头痛、哮喘和特应性疾病;结果变量是随访时的持续LBP（过去一年中> 30天）。结果：1994年发病率与2002年LBP发病率之间的相关性分析表明，青少年期LBP、头痛和哮喘与未来LBP发病率呈正相关。特应性疾病和未来LBP之间没有关联。基线时持续LBP的个体未来LBP的比值比为3.5（2.8 - 4.5），而持续LBP，持续头痛和哮喘的比值比为4.5（2.5 - 8.1）。这些疾病有很大程度的集群，但特应性疾病是不是这个pattery.Conclusion的一部分：年轻人从12岁到22岁，持续性LBP在前一年有一个优势比为3.5持续性LBP八年后。头痛和哮喘也与未来的LBP呈正相关，并且在青春期有大量的LBP，头痛和哮喘聚集。
Background: It has previously been shown that low back pain (LBP) often presents already in the teenage years and that previous LBP predicts future LBP. It is also well documented that there is a large degree of comorbidity associated with LBP, both in adolescents and adults. The objective of this study is to gain a deeper insight into the etiology of low back pain and to possibly develop a tool for early identification of high-risk groups. This is done by investigating whether different types of morbidity in adolescence are associated with LBP in adulthood.Methods: Almost 10,000 Danish twins born between 1972 and 1982 were surveyed by means of postal questionnaires in 1994 and again in 2002. The questionnaires dealt with various aspects of general health, including the prevalence of LBP, classified according to number of days affected during the previous year ( 0, 1 - 7, 8 - 30, > 30). The predictor variables used in this study were LBP, headache, asthma and atopic disease at baseline; the outcome variable was persistent LBP (> 30 days during the past year) at follow-up. Associations between morbidity in 1994 and LBP in 2002 were investigated.Results: LBP, headache and asthma in adolescence were positively associated with future LBP. There was no association between atopic disease and future LBP. Individuals with persistent LBP at baseline had an odds ratio of 3.5 ( 2.8 - 4.5) for future LBP, while the odds ratio for those with persistent LBP, persistent headache and asthma was 4.5 (2.5 - 8.1). There was a large degree of clustering of these disorders, but atopic disease was not part of this pattern.Conclusion: Young people from 12 to 22 years of age with persistent LBP during the previous year have an odds ratio of 3.5 persistent LBP eight years later. Both headache and asthma are also positively associated with future LBP and there is a large clustering of LBP, headache and asthma in adolescence.