Outbreak of hepatitis B in an acupuncture clinic.
Outbreak of hepatitis B in an acupuncture clinic.
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针灸诊所爆发乙型肝炎。
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
D. Carrington
中科院分区：
文献类型：
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作者：
B. Walsh;H. Maguire;D. Carrington
一项回顾性队列血清学研究在伦敦的一家针灸诊所发现了5例急性B型肝炎病毒（HBV）感染的确诊病例。这些病例占接受B e抗原（HBeAg）携带者针灸师治疗的病例的1.7%。病毒分型和聚合酶链反应-单链构象多态性分析（PCR-SSCPA）显示，从针灸师和五个病人中的两个，它是可能进行测试的病毒株是无法区分的。其他9名患者谁出席了同一针灸师有抗体的B型肝炎核心抗原，但有其他风险因素的HBV感染。没有发现明显的传播方式，但在两例病例中不能排除针头交叉污染。第5例在引入一次性针头后暴露于HBV。建议针灸师常规接种乙肝疫苗。
A retrospective cohort serological study identified five confirmed cases of acute hepatitis B virus (HBV) infection in three and a half years at an acupuncture clinic in London. These cases made up 1.7% of those treated by an acupuncturist who was a hepatitis B 'e' antigen (HBeAg) carrier. Virus subtyping and polymerase chain reaction--single strand conformation polymorphism assay (PCR-SSCPA) showed that strains of virus from the acupuncturist and two of the five patients for whom it was possible to perform the test were indistinguishable. Nine other patients who attended the same acupuncturist had antibody to the hepatitis B core antigen but had other risk factors for HBV infection. No obvious mode of transmission was identified but cross contamination of needles could not be ruled out in two cases. The fifth case was exposed to HBV after disposable needles were introduced. Routine immunisation of acupuncturists against HBV is recommended.