Differences in Cognitive Profile between TIA, Stroke and Elderly Memory Research Subjects: A Comparison of the MMSE and MoCA
Differences in Cognitive Profile between TIA, Stroke and Elderly Memory Research Subjects: A Comparison of the MMSE and MoCA
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DOI：
10.1159/000338905
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发表时间：
2012-01-01
影响因子：
2.9
通讯作者：
Rothwell, P. M.
中科院分区：
文献类型：
--
作者：
Pendlebury, S. T.;Markwick, A.;Rothwell, P. M.
背景：蒙特利尔认知评估（MoCA）似乎比迷你精神状态检查（MMSE）对轻度认知障碍（MCI）更敏感：超过50%的TIA和卒中患者MMSE评分为>= 27（“正常”认知功能）在>=指数事件后6个月，评分= 24)具有不同的临床特征：TIA和卒中队列中额叶/执行功能缺陷预计普遍存在，记忆研究队列。方法：在索引事件发生6个月或更长时间后，在一项基于人群的研究（牛津血管研究）中对连续的TIA或中风患者进行MMSE和MoCA，并在一项记忆研究队列（牛津研究记忆和衰老项目）中对连续的受试者进行MMSE和MoCA。中重度认知功能障碍患者（MMSE评分= 27）。结论：与MMSE相比，MoCA在TIA、卒中和记忆研究对象之间的认知特征差异更大。即使在MMSE正常的人群中，MoCA也显示出组间差异，因此似乎是评估MCI患者认知能力的一个有用的简短工具，特别是在MMSE的天花板效应存在问题的情况下。巴塞尔S. Karger股份有限公司版权所有
Background: The Montreal Cognitive Assessment (MoCA) appears more sensitive to mild cognitive impairment (MCI) than the Mini-Mental State Examination (MMSE): over 50% of TIA and stroke patients with an MMSE score of >= 27 ('normal' cognitive function) at >= 6 months after index event, score = 24) with differing clinical characteristics: a TIA and stroke cohort in which frontal/executive deficits were expected to be prevalent and a memory research cohort. Methods: The MMSE and MoCA were done on consecutive patients with TIA or stroke in a population-based study (Oxford Vascular Study) 6 months or more after the index event and on consecutive subjects enrolled in a memory research cohort (the Oxford Project to Investigate Memory and Ageing). Patients with moderate-to-severe cognitive impairment (MMSE score of = 27. Conclusions: The MoCA demonstrated more differences in cognitive profile between TIA, stroke and memory research subjects without major cognitive impairment than the MMSE. The MoCA showed between-group differences even in those with normal MMSE and would thus appear to be a useful brief tool to assess cognition in those with MCI, particularly where the ceiling effect of the MMSE is problematic. Copyright (C) 2012 S. Karger AG, Basel