Effects of Pre-Exercise Voluntary Hyperventilation on Metabolic and Cardiovascular Responses During and After Intense Exercise
Effects of Pre-Exercise Voluntary Hyperventilation on Metabolic and Cardiovascular Responses During and After Intense Exercise
复制标题
运动前自愿过度换气对剧烈运动期间和之后代谢和心血管反应的影响
DOI：
10.1080/02701367.2022.2121371
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发表时间：
2022
影响因子：
2.2
通讯作者：
Nishiyasu Takeshi
中科院分区：
文献类型：
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作者：
Dobashi Kohei;Ichinose Masashi;Fujii Naoto;Fujimoto Tomomi;Nishiyasu Takeshi
目的：探讨运动前自主过度换气及由此引起的低碳酸血症对大强度运动中及运动后代谢和心血管反应的影响。方法：10名健康受试者在对照组(自主呼吸)、低碳酸血症和正常二氧化碳负荷120%的峰值摄氧量下进行60次S单车训练。通过运动前20min自主过度换气诱导低碳酸血症。结果：低碳酸血症患者运动前呼气末二氧化碳分压低于对照组或正常碳酸血症患者，而对照组和正常碳酸血症患者的二氧化碳分压水平相近。在整个运动过程中，低碳酸血症和正常碳酸血症试验的平均降幅均低于对照试验(1491±252比1662±1669比1806±1149mLmin−1)，其中低碳酸血症试验比正常二氧化碳试验表现出更大的降幅。低碳酸血症试验组的运动时每分钟通气量低于正常碳酸血症试验组。此外，在运动的前10秒内，常碳酸组的每分钟通气量低于对照组。与正常碳酸血症试验相比，运动前低碳酸血症也降低了运动期间的心率和动脉血压，这种反应持续到随后的早期恢复期，尽管两个试验中呼气末二氧化碳分压相似。结论：我们的结果表明，高强度运动可以减少运动前高呼吸和由此产生的低碳酸血症。此外，在运动过程中，低碳酸血症可能有助于自主过度换气介导的心血管反应，这种反应可以持续到随后的恢复期，尽管动脉血二氧化碳分压恢复到正常二氧化碳水平。
Purpose:We investigated the effects of pre-exercise voluntary hyperventilation and the resultant hypocapnia on metabolic and cardiovascular responses during and after high-intensity exercise.Methods: Ten healthy participants performed a 60-s cycling exercise at a workload of 120% peak oxygen uptake in control (spontaneous breathing), hypocapnia and normocapnia trials. Hypocapnia was induced through 20-min pre-exercise voluntary hyperventilation. In the normocapnia trial, voluntary hyperpnea was performed with CO2inhalation to prevent hypocapnia.Results: Pre-exercise end-tidal CO2partial pressure was lower in the hypocapnia trial than the control or normocapnia trial, with similar levels in the control and normocapnia trials. Averageduring the entire exercise was lower in both the hypocapnia and normocapnia trials than in the control trial (1491 ± 252vs.1662 ± 169vs.1806 ± 149 mL min−1), with the hypocapnia trial exhibiting a greater reduction than the normocapnia trial. Minute ventilation during exercise was lower in the hypocapnia trial than the normocapnia trial. In addition, minute ventilation during the first 10s of the exercise was lower in the normocapnia than the control trial. Pre-exercise hypocapnia also reduced heart rates and arterial blood pressures during the exercise relative to the normocapnia trial, a response that lasted through the subsequent early recovery periods, though end-tidal CO2partial pressure was similar in the two trials.Conclusions: Our results suggest that pre-exercise hyperpnea and the resultant hypocapnia reduceduring high-intensity exercise. Moreover, hypocapnia may contribute to voluntary hyperventilation-mediated cardiovascular responses during the exercise, and this response can persist into the subsequent recovery period, despite the return of arterial CO2pressure to the normocapnic level.