Effect of biogenic fermentation impurities on lactic acid hydrogenation to propylene glycol.
Effect of biogenic fermentation impurities on lactic acid hydrogenation to propylene glycol.
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DOI：
10.1016/j.biortech.2007.10.027
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发表时间：
2008-09
影响因子：
11.4
通讯作者：
Zhigang Zhang;J. E. Jackson;Dennis J. Miller
中科院分区：
文献类型：
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作者：
Zhigang Zhang;J. E. Jackson;Dennis J. Miller
考察了葡萄糖发酵生成乳酸（LA）过程中残留杂质对随后的乳酸（LA）催化氢化生成丙二醇（PG）的影响。尽管精制的LA进料在滴流床反应器中在碳负载的钌催化剂上表现出稳定的PG转化率，但来自发酵的部分精制的LA在短（<40小时）反应时间内显示出PG产量的急剧下降，随后是性能的进一步缓慢衰减。添加模型杂质精制LA有不同的影响：有机酸，糖，或无机盐转化率几乎没有影响;丙氨酸，模型氨基酸，结果在一个强大的，但可逆的下降，通过竞争性吸附之间的转化率丙氨酸和LA的Ru表面。含硫氨基酸半胱氨酸和甲硫氨酸不可逆地毒害LA转化的催化剂。添加0.1wt%白蛋白作为模型蛋白导致速率缓慢下降，与孔堵塞或组合孔堵塞和Ru表面中毒一致。这项研究指出，需要在生物炼制的生物工艺和化学工艺的集成设计和操作，以使有效的转换方案可行。
The effect of residual impurities from glucose fermentation to lactic acid (LA) on subsequent ruthenium-catalyzed hydrogenation of LA to propylene glycol (PG) is examined. Whereas refined LA feed exhibits stable conversion to PG over carbon-supported ruthenium catalyst in a trickle bed reactor, partially refined LA from fermentation shows a steep decline in PG production over short (<40h) reaction times followed by a further slow decay in performance. Addition of model impurities to refined LA has varying effects: organic acids, sugars, or inorganic salts have little effect on conversion; alanine, a model amino acid, results in a strong but reversible decline in conversion via competitive adsorption between alanine and LA on the Ru surface. The sulfur-containing amino acids cysteine and methionine irreversibly poison the catalyst for LA conversion. Addition of 0.1wt% albumin as a model protein leads to slow decline in rate, consistent with pore plugging or combined pore plugging and poisoning of the Ru surface. This study points to the need for integrated design and operation of biological processes and chemical processes in the biorefinery in order to make efficient conversion schemes viable.