Preparation of poly(serine ester)s by ring-opening polymerization of N-trityl serine lactone under catalysis of ZnEt2
Preparation of poly(serine ester)s by ring-opening polymerization of N-trityl serine lactone under catalysis of ZnEt2
复制标题
ZnEt2催化N-三苯甲基丝氨酸内酯开环聚合制备聚丝氨酸酯
DOI：
10.1007/s40242-013-2355-9
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发表时间：
2013
影响因子：
3.1
通讯作者：
Yubin Huang
中科院分区：
文献类型：
--
作者：
Ying Wei;Xiaoyuan Li;X. Jing;Xuesi Chen;Yubin Huang
Poly(N-trityl serine lactone)(PTSL) and mPEG-block-poly(N-trityl serine lactone)(mPEG-b-PTSL, PEG=polyethylene glycol) were synthesized via the ring-opening polymerization of N-trityl serine lactone(TSL) with diethyl zinc(ZnEt2) as catalyst. The structures of these polymers were confirmed with hydrogen nuclear magnetic resonance(1H NMR) spectroscopy, carbon nuclear magnetic resonance(13C NMR) spectroscopy and infrared(IR) spectrometer. The thermal decomposition temperature and glass transition temperature of PTSL were 241 and 161 °C, respectively. A series of mPEG-b-PTSL with different molecular weights(Mn’s from 7000 to 32000) was obtained by tuning the TSL/mPEG feed ratio. After the removal of the trityl groups, mPEG-block-poly(serine lactone)(mPEG-b-PSL) was obtained as a new kind of cationic block copolymer. Low cytotoxicity of these polymers to L929 cells was confirmed via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay.
影响因子：
10.8
作者：
Li, ZH;Huang, L
通讯作者：
Huang, L
DOI：
10.1002/jbm.820291105
发表时间：
1995-11
期刊：
Journal of biomedical materials research
影响因子：
--
作者：
S. Ertel;J. Kohn;M. Zimmerman;J. Parsons
通讯作者：
S. Ertel;J. Kohn;M. Zimmerman;J. Parsons
DOI：
10.1002/jbm.820280811
发表时间：
1994-08-01
期刊：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
影响因子：
--
作者：
ERTEL, SI;KOHN, J
通讯作者：
KOHN, J