Regional Cerebral Blood Flow Measurement Using Tc‐99m HMPAO SPECT in a Patient With Adrenoleukodystrophy
Regional Cerebral Blood Flow Measurement Using Tc‐99m HMPAO SPECT in a Patient With Adrenoleukodystrophy
复制标题
使用 Tc-99m HMPAO SPECT 测量肾上腺脑白质营养不良患者的局部脑血流
DOI：
10.1097/00003072-199501000-00013
复制
发表时间：
1995
影响因子：
10.6
通讯作者：
A. Yagishita
中科院分区：
文献类型：
--
作者：
H. Matsuda;H. Uesugi;Kazuhiko Kamata;N. Sunohara;A. Yagishita
Regional cerebral blood flow (rCBF) measurement using Tc-99m HMPAO angiography and SPECT was performed in a patient with adrenoleukodystrophy. The whole brain CBF showed great reduction to 31 ml/100 g/min as compared with an age-matched normal value of 45.9 ml/100 g/min. rCBF showed extremely decreased values of approximately 28 and 10 ml/100 g/min in bilateral frontal cortex and white matter respectively. The SPECT scan provided useful information on gray matter involvement to MRI findings of widespread white matter lesions. This quantitative nuclear medicine technique may contribute to pathophysiologic evaluation of adrenoleukodystrophy complementary with MRI.
