FUNCTIONAL ADAPTATION IN LONG BONES - ESTABLISHING INVIVO VALUES FOR SURFACE REMODELING RATE COEFFICIENTS
FUNCTIONAL ADAPTATION IN LONG BONES - ESTABLISHING INVIVO VALUES FOR SURFACE REMODELING RATE COEFFICIENTS
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DOI：
10.1016/0021-9290(85)90022-3
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发表时间：
1985-01-01
影响因子：
2.4
通讯作者：
KOHN, DH
中科院分区：
文献类型：
--
作者：
COWIN, SC;HART, RT;KOHN, DH
在本文中，我们描述了一种基于梁理论的计算方法，用于将自适应弹性理论应用于真实骨骼几何形状的示例。动物实验的结果取自文献，每个实验都记录了骨骼机械载荷环境发生显着变化后骨骼形状变化的时间演变。对于每一项研究，我们都对表面重塑率系数的体内值进行了初步估计，表面重塑率系数是表面重塑理论中的关键参数。我们的初步参数估计是通过将已发表的动物实验结果与计算方法生成的表面重塑理论预测进行比较而建立的。
In this paper we describe a computational means, based on beam theory, for application of the theory of adaptive elasticity to examples of real bone geometries. The results of the animal experiments were taken from the literature, and each documented the temporal evolution of a change in bone shape after a significant change in the mechanical loading environment of the bone. For each of these studies, we establish preliminary estimates of the in vivo values of the surface remodeling rate coefficients-the key parameters in the theory of surface remodeling. Our preliminary parameter estimates are established by comparison of published animal experimental results with surface remodeling theory predictions generated by the computational method.