Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study.

Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study.
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身高和体重作为儿童基础血压的决定因素——Bogalusa 心脏研究。

DOI:
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发表时间:
1977
影响因子:
5
通讯作者:
Gerald S. Berenson
Gerald S. Berenson
中科院分区:
医学2区
文献类型:
--
作者:
A. Voors;L. S. Webber;Ralph R. Frerichs;Gerald S. Berenson

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身高和体重是儿童基础血压的决定因素--博加卢萨心脏研究美国流行病学杂志106:101-108,1977年。在一项对3524名5-14岁儿童进行的全方位社区研究中,测量了冠状动脉疾病的危险因素变量。人体测量变量,血脂和血压(BP)的测量采用严格的随机设计。使用自动记录仪获得血压数据,该自动记录仪通过使用带有内置次声换能器的超大臂袖囊来避免肥胖儿童的过度压力读数。通过减少孩子的焦虑和采取多个读数,压力接近公布的基础水平。多元回归分析表明,所有测量变量可以解释收缩压变化的39%。主要决定因素是体重(W)和身高(H)。当与H和体重-身高指数(W/H3)相关时,BP水平表明H对BP的强烈影响和W/H3对BP的额外影响,在H和W/H3的整个范围内一致且成比例。从多元回归分析中观察到的BP相关性的总谱表明,在基础条件下测量的BP随着儿童的生长而增加,并且与瘦体重和总体重成比例。评估儿童血压异常水平的实用标准应基于体重和身高的标准值,而不是年龄。
Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study. Am J Epidemiol 106:101-108, 1977. Risk factor variables for coronary artery disease were measured in a total biracial community study of 3524 children, ages 5-14 years. Anthropometric variables, serum lipids, and blood pressure (BP) were measured in a rigid randomized design. Blood pressure data were obtained with an automatic recording instrument that avoids excessive pressure readings in obese children by the use of an over-sized arm cuff bladder with a built-in infrasonic transducer. By reducing the anxiety of the child and by taking multiple readings, pressures were obtained that approached published basal levels. A multiple regression analysis showed that all measured variables could account for 39% of the systolic BP variation. Major determinants were based on weight (W) and height (H). The BP levels, when related to H and to a weight-height index (W/H3), suggest a strong influence of H and an additional influence of W/H3 on BP, both consistent and proportionate over the entire ranges of H and W/H3. The total spectrum of observed correlates of BP, resulting from the multiple regression analysis, suggests that the BP measured under basallike conditions increases as the child grows and is proportional to lean body mass and total body mass. Practical criteria for evaluating abnormal blood pressure levels in children should be based on normative values derived from body weight and body height rather than from age.