Quantitative analysis of aldosterone's role in potassium regulation.
Quantitative analysis of aldosterone's role in potassium regulation.
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醛固酮在钾调节中的作用的定量分析。
DOI：
10.1152/ajprenal.1988.255.5.f811
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Young,DB
中科院分区：
文献类型：
--
作者：
Young,DB
醛固酮是一个复杂系统的一部分，该系统通过影响钾离子的肾脏排泄及其在体内的分布来调节血浆钾浓度。由于该系统还有其他组成部分，很难通过单独研究醛固酮的作用来确定其在钾调节中的生理意义。在本报告中，钾控制系统的定量分析用于提供有关正常和病理条件下醛固酮在钾调节中的生理作用的信息，以及在药物干预期间。
Aldosterone is part of a complex system that regulates plasma potassium concentration by affecting the renal excretion of the ion as well as its distribution within the body. Because there are other components of the system, it has been difficult to determine the physiological significance of aldosterone in potassium regulation by attempting to study the hormone's effects in isolation. In this presentation a quantitative analysis of the potassium control system is used to provide information concerning the physiological role of aldosterone in potassium regulation under normal and pathological conditions, as well as during pharmacological interventions.