Who mixes with whom? A method to determine the contact patterns of adults that may lead to the spread of airborne infections
Who mixes with whom? A method to determine the contact patterns of adults that may lead to the spread of airborne infections
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DOI：
10.1098/rspb.1997.0131
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发表时间：
1997-07-22
影响因子：
4.7
通讯作者：
Nokes, DJ
中科院分区：
文献类型：
--
作者：
Edmunds, WJ;OCallaghan, CJ;Nokes, DJ
据我们所知，尽管混合模式被认为是空气传染病传播的重要决定因素，但没有试图直接量化它们的人类。我们报告了一项初步研究，以识别这种混合模式。要求92名成年人的样本详细介绍他们在一个随机分配的时期中与之交谈的个人。六十五（71％）完成了问卷，提供了他们的年龄，联系的年龄和联系的社会环境。使用多级建模分析数据。该研究确定并允许对本样本中可能具有流行病学意义的接触模式进行定量。例如，相对于年龄的混合的分类程度不仅取决于参与者的年龄，而且取决于进行的接触次数。对不同社交环境之间的接触率相对大小的估计，对爆发潜力产生了影响。提出了简单的问卷修改，这将产生有关社交网络结构和动态的信息和接触强度。对这种性质的调查可以量化谁从谁和哪里获得感染。
Although mixing patterns are thought to be important determinants of the spread of airborne infectious diseases, to our knowledge, there have been no attempts to directly quantify them for humans. We report on a preliminary study to identify such mixing patterns. A sample of 92 adults were asked to detail the individuals with whom they had conversed over the period of one, randomly assigned, day. Sixty-five (71%) completed the questionnaire, providing their age, the age of their contacts and the social context in which the contacts took place. The data were analysed using multilevel modelling. The study identified, and allowed the quantification of, contact patterns within this sample that may be of epidemiological significance. For example, the degree of assortativeness of mixing with respect to age was dependent not only on the age of participants but the number of contacts made. Estimates of the relative magnitude of contact rates between different social settings were made, with implications for outbreak potential. Simple questionnaire modifications are suggested which would yield information on the structure and dynamics of social networks and the intensity of contacts. Surveys of this nature may enable the quantification of who acquires infection from whom and from where.