Filter and cassette mass instability in ascertaining the limit of detection of inhalable airborne particulates.
Filter and cassette mass instability in ascertaining the limit of detection of inhalable airborne particulates.
复制标题
确定可吸入空气颗粒物检测限时的过滤器和盒式质量不稳定性。
DOI：
10.1080/15428110208984757
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
Vincent,JamesH
中科院分区：
文献类型：
--
作者：
Paik,Samuel;Vincent,JamesH
在工作场所气溶胶的重量评估中，越来越需要可靠地测量越来越小的收集质量。为此，重要的是要了解所进行分析的检测限（LOD）和定量限（LOQ），通过称量空白样品的不精密度确定。目前特别感兴趣的是可吸入气溶胶的测量，如美国政府工业卫生学家会议阈值限值清单中对许多物质所定义的。一种流行的方法是使用包含在小盒子中的过滤器，其中两者都被称重。对塑料和不锈钢卡匣的早期研究表明，塑料卡匣对湿度变化高度敏感。但一项研究也表明，由此产生的质量变化可以在很大程度上通过使用场空白来纠正。因此，进行了一项调查，以确定各种卡匣和过滤器组件的称重不精密度，假设进行了空白校正。研究了三种类型的过滤器（Teflon®、玻璃纤维和聚氯乙烯）与三种类型的卡匣（塑料、镀镍塑料和不锈钢）的组合。结果表明，无论使用何种底物，均可以分别可靠地检测和定量等于或高于0.19和0.65 mg的样品质量。
In the gravimetric assessment of workplace aerosols, there is an increasing need to confidently measure smaller and smaller collected masses. To do this, it is important to know both the limit of detection (LOD) and limit of quantification (LOQ) of the analysis performed, determined by the weighing imprecision of blank samples. Of particular current interest is the measurement of inhalable aerosols, as defined for many substances in the American Conference of Governmental Industrial Hygienists threshold limit values list. One popular method is the use of a filter contained within a small cassette, in which both are weighed. Earlier investigations of plastic and stainless steel cassettes showed that plastic cassettes are highly sensitive to changes in humidity. But one study also demonstrated that the resulting changes in mass could be largely corrected using field blanks. An investigation, therefore, was undertaken to determine the weighing imprecision of various cassette and filter assemblies, assuming blank corrections are made. Three types of filter (Teflon®, glass fiber, and polyvinyl chloride) were investigated in combination with three types of cassette (plastic, nickel-plated plastic, and stainless steel). Results show that regardless of the substrate being used, sample masses equal to or higher than 0.19 and 0.65 mg can be confidently detected and quantified, respectively.