Lineage-specific amino acid substitutions in region 2 of the RNA polymerase σ subunit affect the temperature of promoter opening
Lineage-specific amino acid substitutions in region 2 of the RNA polymerase σ subunit affect the temperature of promoter opening
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DOI：
10.1128/jb.00008-08
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发表时间：
2008-04-01
影响因子：
3.2
通讯作者：
Kulbachinskiy, A.
中科院分区：
文献类型：
--
作者：
Barinova, N.;Zhilina, E.;Kulbachinskiy, A.
已知RNA聚合酶或亚基的区域2中的高度保守的氨基酸残基参与启动子识别和打开。我们证明，在这一地区的非保守残基共同决定启动子开放的温度的谱系特异性差异。
Highly conserved amino acid residues in region 2 of the RNA polymerase or subunit are known to participate in promoter recognition and opening. We demonstrated that nonconserved residues in this region collectively determine lineage-specific differences in the temperature of promoter opening.