Geometric characterization of polymeric capillaries
Geometric characterization of polymeric capillaries
复制标题
聚合物毛细管的几何表征
DOI：
10.1016/j.aca.2022.340345
复制
发表时间：
2022
影响因子：
6.2
通讯作者：
Roy, Souvik
中科院分区：
文献类型：
--
作者：
Yousef, Enas N.;Dasgupta, Purnendu K.;Horn, Seth A.;Shelor, C. Phillip;Roy, Souvik
文献中很少有测量非常小的毛细血管内径的方法。虽然二氧化硅毛细管更常用，但在某些应用中优选合成聚合物毛细管。生产它们的技术还不成熟。除了内径的绝对值之外，这种毛细管的圆度、同心度（这里首次定义了定量指标）和孔均匀性也是令人感兴趣的。除了显微镜，我们描述了多种方法，确定毛细管内径，平均超过一个给定的长度。测量结果不同地取决于毛细管的内部体积、长度和横截面以及对流体流动的阻力。不同的方法产生了相互一致的结果。我们表明，当内径是不均匀的，不同的依赖于直径，这两种方法可能会表现出，可以利用确定真正的平均直径，以及它的方差。最后，对于开管液相色谱，其中性能严重依赖于内径，我们惊讶地发现，虽然平均i. d.可能是效率的主要决定因素，但内径变化对性能几乎没有影响。
There are few methods in the literature to measure the inner diameter of very small capillaries. Although silica capillaries are more commonly used, synthetic polymer capillaries are preferred in some applications. The technology for producing them is not as mature. Aside from the absolute value of the inner diameter, the circularity, concentricity (a quantitative index is defined here for the first time) and the bore uniformity of such capillaries are of interest. Beyond microscopy, we describe multiple methods that determine the capillary inner diameter, averaged over a given length. The measurements variously depended on the capillary internal volume, length and cross section, and the resistance to fluid flow. The different approaches produced mutually consistent results. We show that when the internal diameter is not uniform, the different dependence on diameter that two such methods may exhibit, can be exploited to determine the true mean diameter as well as its variance. Finally, for open tubular liquid chromatography, where performance acutely depends on the inner diameter, we surprisingly find that while the mean i.d. may be the dominant determinant of efficiency, bore variance has little to no effect on the performance.