Randomized controlled trial of cognitive behavioral stress management in breast cancer: a brief report of effects on 5-year depressive symptoms.
Randomized controlled trial of cognitive behavioral stress management in breast cancer: a brief report of effects on 5-year depressive symptoms.
复制标题
乳腺癌认知行为压力管理的随机对照试验：对 5 年抑郁症状影响的简要报告。
DOI：
10.1037/hea0000125
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
Carver,CharlesS
中科院分区：
文献类型：
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作者：
Stagl,JamieM;Antoni,MichaelH;Lechner,SuzanneC;Bouchard,LauraC;Blomberg,BonnieB;Glück,Stefan;Derhagopian,RobertP;Carver,CharlesS
目的乳腺癌幸存者会经历压力，并且在初次治疗后有出现抑郁症状的风险。此前，在 12 个月的随访中，针对非转移性乳腺癌 (BCa) 进行的术后认知行为压力管理 (CBSM) 等基于团体的干预措施与较少的抑郁症状相关。很少有研究探讨此类心理社会干预措施的长期益处。这项针对先前进行的试验 (# NCT01422551) 的 5 年随访研究测试了非转移性 BCa 手术后基于群体的 CBSM 是否与较少的抑郁症状相关。方法 0-IIIb 期 BCa 女性 (N = 240) 在术后 2-10 周被招募，并随机分配到为期 10 周的 CBSM 干预组或为期 1 天的心理教育对照组。研究入组后 5 年重新联系女性并重新同意参加后续研究 (N= 130)。使用流行病学研究中心抑郁量表（CES-D）评估抑郁症状。采用方差分析和方差分析来检验 5 年随访时 CES-D 上的组间差异，以解释相关协变量。 结果分配至 CBSM 的参与者在随访时报告的抑郁症状 (M = 9.99，SE = 0.93) 与对照组相比 (M = 12.97，SE = 0.99) 显着减少，p =。 030. 对于协变量，组间差异仍然显着，p=。 012. 结论 在 5 年随访中，接受 CBSM 术后 BCa 治疗的女性抑郁症状少于对照组。治疗早期的社会心理干预可能会影响BCa幸存者的长期心理健康。
ObjectiveSurvivors of breast cancer experience stress and are at risk for depressive symptoms following primary treatment. Group-based interventions such as cognitive–behavioral stress management (CBSM) delivered postsurgery for nonmetastatic breast cancer (BCa) were previously associated with fewer depressive symptoms over a 12-month follow-up; few studies have examined the longer-term benefits of such psychosocial interventions. This 5-year follow-up study of a previously conducted trial (# NCT01422551) tested whether group-based CBSM following surgery for nonmetastatic BCa was associated with fewer depressive symptoms.MethodsWomen (N= 240) with Stage 0-IIIb BCa were recruited 2–10 weeks postsurgery and randomized to a 10-week CBSM intervention group or a 1-day psycho-educational control group. Women were recontacted 5 years poststudy enrollment and reconsented to participate in the follow-up study (N= 130). Depressive symptomatology was assessed using the Center for Epidemiologic Studies-Depression scale (CES-D). ANOVA and ANCOVA analyses were employed to test for group differences on the CES-D at 5-year follow-up accounting for relevant covariates.ResultsParticipants assigned to CBSM reported significantly fewer depressive symptoms (M= 9.99, SE= 0.93) at the follow-up compared with those in the control group (M= 12.97, SE= 0.99), p=. 030. With covariates, the group difference remained significant, p=. 012.ConclusionWomen who received CBSM postsurgery for BCa reported fewer depressive symptoms than those in the control group in this 5-year follow-up. Psychosocial interventions early in treatment may influence long-term psychological well-being in BCa survivors.